Sneeze symptoms and conditions

We have all been saying that our issues regard not being informed about all of the possible side effects. And, we know that Singulair works well for some people. Nobody wants to take a good drug away from those for which it probably performs miracles. People who have toxic side effects have a right to know up front.

My observations about montelukast's chemical structure are either general or not quite 100% correct or could be quite vague - so forgive me. I do not claim to be good at organic chemistry. But from doing a little work, I have come up with some observations.

1. It would seem to me that montelukast might work quite well for people who have developed mold category related asthma. I observed that chloroquinolin, a component of montelukast, is a good fungicide effective against Aspergillus, Alternaria, Cladosporium, Penicillium and Candida. Dust mites can only digest if helped by aspergillus so they go into the mold category. Molds produce millions of spores so anyone who lives in contact with mold would be chronically sick from their presence. Then people get hypersensitized to that.

I am probably wrong but I could imagine that montelukast is: 1) a ligand that binds to an empty cysLT1 receptor for a period of time 2) 7-chloroquinolin-2-yl which either acts intact or breaks down into a quinoline fungicide so that it kills the chronic mold/fungus infection and 3) a sulphur/methyl anti-inflammatory component that tells the t-cells that they are not needed so they will die. Wow, that would be great for mold asthma if it was completely non-toxic. It would be also great under controlled circumstances for many people who are mold-miserable. If I am wrong, I better go out into my garage and start inventing such a drug.

This is my visualization to try to explain the side effects of neurotoxicity. So adverse reactions could be to the quinoline component as an allergic reaction or dose related so that it just built up to a toxic level over time. There are many signs that t-cell populations are significantly reduced by montelukast. The fact that the Italians can do it in the test tube might be that it's a chemical component of montelukast designed to cause the t-cells to die.

Montelukast is a large molecule so Artie says it cannot penetrate the blood brain barrier. That would be an argument if nobody was complaining about neuro-psychiatric side effects. The neuro-psychiatric side effects are identical to quinoline and quinolones. When I read about Lariam, it just sounds like a more extreme version of Singulair side effects. Chloroquinolins were used before they invented Lariam, which is stronger. The malaria Plasmodiums became immune. Hallucinations, anxiety, depression, suicidal thoughts are completely consistent in all of the quinoline/quinolones. If montelukast breaks into sub-molecules then quinolines easily penetrate the blood brain barrier.

I find clinical evidence that montelukast may act as more than more molecule. And, that there is a rational for the existence of the chloroquinolin and evidence that it may be the source of toxicity.

I am glad to risk being called crazy. That is what the internet is for. We can present our ideas and discuss. So, just take this with a grain of salt. If I am close to the truth, this post will find it's proper home.

27 yr old healthy male. Have red-irritated eyes, occasional sneeze and runny nose, live in Denver (highly polluted). Come to think about it, never started having symptoms until after about 1 yr of living here. Symptoms have persisted for 2 yrs now. Maybe I should move?

doctor thought was allergies, so tried: Patanol, Singulair, Claritin, Duramist = no help. Eyes are still itchy, eyelids are embarrassingly red (I look like I'm high all the time). After 4 months on Singulair, noticed significant weight gain, dehydration, and sensitivity to light. Couldn't work out, play paint ball. Urine was always dark yellow. Singulair seemed to help at first, but as time went on, symptoms were worse and had additional problems, weight gain, etc. Things seemed to be spiraling out of control, and I am really depressed b/c there seems to be no solution.

I complained of some loss of vision (i.e. blurriness, hard to focus), so doctor sent me to ophthalmologist. They prescribed glasses and said I have dry eye like that person posted on Nov 18th. They told me to wash my eyes with baby soap. No help! These people have no idea what to do, I got fed up and quite taking Singulair after reading this website. I hope to lose weight and start working out again. I can't believe that doctors prescribe Singulair and have no idea (NO IDEA!) of all of us who must suffer from this terrible drug.

I don't do drugs, drink occasionally and have really cut down trying to get this problem solved. I have become sensitive to caffeine, if I drink coffee, my eyes hurt so bad, I can hardly keep them open. I'm going to do as much research as I can to find a solution. I trusted my doctors - bad idea!

I have been on Lisinopril fro 6 months. AT 1st 1 felt horrible like most of the symtoms already mentioned (tired, heart palpitations,etc) Most side effects have subsided after about a month or so, EXCEPT this tickle cough that started within days of taking it and is driving me crazy! I have stress incontinence to begin with (pee when I sneeze or cough) but nothing that a thin panty liner worn every day to take of the problem. This cough is constant..all night long, during the day...I am so tired of that feather tickle in my throat..and it goes without saying that my stress incontinence is much worse..that panty liners no longer are large enough to control that problem! Thank goodness I have a doctors appt tomorrow...I refuse to stay on this medication even though it has done great for my BP

I was just at the Optomalogist's office 6/19/07 for seven hours and ER for five hours. I was being treated for Acute Angle Closure Glaucoma.
Started with a sneeze on 6/19 a.m. that brought on blurry vision in right eye. As the day progressed both eyes became affected. Pressure in right eye was 51 and pressure in left eye was 50. (pressure should be between 12-15) Eye Doctor tried to bring down eye pressure by giving me Diamox 250 mg and drops of Istalol and Alphagan (ended up getting a full 1000 mg of Diamox) before they set me to the ER for an I.V. of Mannitol to deliver medicine faster, which brought down my pressure to right 32 and left 28. Back at Eye Dr's 6/20 pressure is down to right 20 and left 22.
Will follow up again with them on Friday. This is all due to me taking 25 mg. of Topamax for the last three weeks for Migraines. Surgery would of been my next option if the I.V. did not work. They were talking about using a laser to cut a hole in my eye to relieve the pressure. Still have blurry vision today but it is slowly coming back. I wanted to find out about other people with the same type of problem as me.

Hi,My biggest side effects are the hair loss,limb swelling,insomnia,halucinations(unless my dead dog really is a ghost),memory loss,numbness in legs and arms,tingling in arms and hands expecially when I cough or sneeze,sinus stuffiness and infections and cronic bronchitis.Allthough I have these side effects I personally think that I am better off taking the singulair for my asthma(does not help my allergy symptoms at all) than when I was on all the allergy meds and streoids.I used to have a bag load of those and I was allways having attacks,was depressed and thought of suicide but then I did the study for singulair about 15 years ago and thought it was a miracle cure so I waited for it to come out on the market.I know it is not a miracle cure but I don't have to take those other meds anymore and I only use my fast acting inhailer mabee once a month now.I am now 6 months pregnant and will be looking for an alternative treatment from a hollistic/natural Dr. after I have the baby.There has got to be a better way to control this disease,I hope,naturally through diet and other remadies with less or no side effects to treat my allergies and asthma.If anyone knows of such tratments,please post it.Thanks.LR

I too have been on Lisinopril for about 9 months. Over that time I have had the dreaded dry cough which usually kicks in out of nowhere lasting a few minutes. This usually happens when in business meetings. I will usually cough a while and then I sneeze. This seems to end the cough. At night the cough is usually triggered by the dry forced hot air my house produces. I stopped taking it on the advise of an Internal Medicine Doctor not the Endocronologist that origionally prescribed it. I am waiting for the cough to go away. After a few weeks he plans to switch me over to Avapro.
I have been a serious cigar smoker for the past 30 years, but over the past few months I have not been able to partake in my favorite passtime. Too painful. Maybe this is a good thing?

I have been on Lisinopril/HCTZ 20mg for about a month. I have severe fatigue, trouble sleeping, cough, sneeze and have a hideous rash on both arms that itches and is spreading to my back and shoulders. Saw my MD yesterday and he thinks I might be alergic to HCTZ (tried to tell him I was on that for 6 years --no rash -- no side effects) he has now prescribed Linisopril with nothing added. If this has not cleared in one week I'm going off the Lisinopril. I'm wondering what this drug is dooing to my vital organs. Do you think the reaction is confined to just the outside of the body?? I don't.
Luckylady1

I'd rather have allergies than take this medication again. Actually, I'm going to appeal for an Rx for Allegra, which gave me no problem.
The side eeks from Singulair I experienced were: clenched teeth, hard time falling asleep, racing thoughts, awful body aches, hard time waking up and a feeling of general malaise.
I'm sure this drug works miracles for some folks, but for me? I'd rather sneeze and drip.

About a week or so into taking Singulair for asthma and allergies, I thought it was an absolute miracle drug! I am extremely allergic to cats and when I am anywhere near them I get horrible asthma and allergies which in several cases sent me to the hospital. The ultimate test was after taking singulair I was able to spend the weekend with my friend in her small apartment and 2 cats without even a sneeze. We couldn't believe it given my past. However, it was too good to be true. Around the same time I noticed pretty dramtic hair loss. At first I just thought I was brushing too hard, I couldn't fathom actually losing my hair. However, it become so dramtic it was coming out in handfulls and I wasn't the only one to notice or be alarmed by this. I immediately stopped the medication but lost close to 70% of my hair as a result of taking singulair. I've read about this happening to others but Singulair and my doctor deny it.

I am 35 yr old female and have been on Singulair for at least 3 years, maybe 4. I stopped taking it 3 weeks ago and I am feeling better than I have in ages. I had no idea there were so many side effects until I started reading the posts here. I had read on packaging inserts about the higher incidents of Singulair causing ear and respiratory infections. I have had numerous infections in the time I have been on this med. I have also had problems with nightmares, teethgrinding, tension in the jaw area and severe headaches. Now I read that others taking Singulair are experiencing the same! The nightmares are terrifying and vivid, something that had not troubled me before. I recently found out I have elevated liver enzymes which the dr cannot figure out why. I now suspect it might be the Singulair or even the combination of taking it with Zyrtec. I really wish I could get off Zyrtec, but I sneeze non-stop and itch like crazy the three times I have tried to stop. Help!

i have been having dizzy feelings, my sinuses hurt worse, and i sneeze very often.

When I sneeze activating contractions of skeletal muscles in the posterior lumbar region and deltoids would cause sharp sensations of pain and resluting sorness.

The past three days I have been taking chewable papain after meals or after eating. I take atenolol for high blood pressure. Last night and today I feel like I have not taken any atenolol. I am wondering if the papaya enzyme has canceled out the atenolol when I took both at the same time. My blood pressure went up from 125 to about 155...enough to interfere with my sleep. Also I have a condition called costocondritis (sp?) which inflames the cartilige in the breastbone area...sometimes bad enough for medication and sometimes not at all. If I sneeze a lot it is especially irritating. Would there be a connection between inflamation in the chest area and papaya?

I was at the end of an MRI session when the doctor asked for one more picture. They inserted an IV and dripped in Prohance and stuck me back in the MRI machine. Within a minute I was sneezing uncontrollably, continuing to sneeze for about two minutes. My throat felt very rough, my ears burned. When they took me out of the machine, my voice (normally a bass speaking voice) was at least an octave higher and sounded frayed and pretty much shot. I also was very dizzy. They hastily pulled out the Prohance tube and started feeding me Benadryl via IV. I had no more sneezing and started feeling better, but the dizziness continued. Fortunately, a friend was with me to drive me home. The dizziness lessened over the next several hours, and my voice slowly returned to normal. But it was at least 12 hours before I felt really normal.

I'm waiting for my doctor to call me back - it's a Friday around 3 p.m. so I probably won't hear from him until Monday. BUT I AM SO EXCITED!! I really feel that I have discovered the cause of my chronic coughing. Here's the lowdown: I had been taking Diovan for a few years, along with another blood pressure med. All was fine. Then we had to change medical coverage and the Diovan was not approved, so shortly after the first of the year (2004) I started taking Lisinopril. I've had an awful time, but I didn't know why until today. I had bronchitis in November '03, then again in February '04. So I was already coughing when I started Lisinopril. I coughed incessantly. Now I realize that I was coughing both from bronchitis AND from the constant tickle in my throat. About 10 days after the Feb. bout of bronchitis began I was in awful pain in the right side of my rib cage. Had lung xrays, rib xrays. Lungs clear. No fracture could be seen, but I was told that 25% of rib fractures do not show up on xray. I was prescribed Hydrochodone for pain, but I took 2 pills and that was the end of those pills. I have to drive & work, and could not function. I am still coughing, but not from my chest as would be the case with bronchitis. It's been driving me crazy, and people at work are somewhat annoyed because I cough all day. TODAY WAS MY LUCKY DAY. All this time I had been trying to determine why I was still coughing from bronchitis. When I got on the Internet & typed in "scratchy throat coughing" I got lots of things that said Lisinopril could be the cause. Then I found your forum and I could not believe it!! I'm ecstatic because I'm sure this has been the problem with my dry, hacking cough - just like some of you, it makes me gag, then my eyes water which makes me sneeze, etc. I will get back to this forum for a final confirmation, but thanks to all of you for taking the time to write your comments. It has been a huge help to me. Bless you all.

i woke up mon july 7th with a cold and then tues july 8th i felt horrible, so much pressure in my head, bad sore throat, wanting to gag and maybe throw up, severe pain in my chest especially when i cough or sneeze, it hurt so bad i felt like crying every time i would, i had to blow my nose every 5 seconds and on top of all that i can't sleep cause i'll cough or my nose would run so bad i had to stuff tissue up there and leave it. also on top of all that mess this was the week i had to work mon-fri at 12 hrs a day since my bosses were up north all week. i went to the docter that tues (8th), i thought maybe i could kill it before it got bad. my doc checked me out, did x-rays and i had the first satage of phemonia. total bummer since i haven't had a cold in two years. my doc gave me levaquin 500mg and tussi-12, i went home that day at 4 pm, sleep, woke up around 8pm ,went for ice cream (sore throat), sleep at 12:30am and i have to say i got great sleep that night, next i felt good 9th, same thing that night too, next day 10th felt even better, everything was clearing up already it was amazing to me, no pain in my chest, barely had to blow my nose, gunk in my chest was clearing up, everything everyone has been complaining about didn't happen. it is the 13th and i feel great besides a little cough here & there & at night but a little nyquil kicks that in the butt & some tiredness but i am truly impressed with this drug i don't want to use all of it so when i have cold again i can get rid of it fast but i have too. the only complaint i do have is that my doctor didn't explain any side effects or good effects she just said take this once a day. maybe doctors fail to tell people the risk of side effects cause their so bad people won't want take. i usually can't get over a cold for 2-3 weeks so i love this stuff. thanx

I went to a Naturopath yesterday, fed up with MD's and their PA's! He did a simple urine test that found a lot of blood in the urine. They sent it to the lab and I will get the results today. I have had bad lower right back pain since March 2nd; plus a different neck, back and rib pain that persisted from 2/12 to 2/28 that now comes and goes.

The lower back pain that started 3/2/03 makes it hurt to take a deep breath, sneeze, bend over, or lie on my right side, but it does not hurt to press in that area???!!! It is between the ribs and hip, more to the back than to the side.

A week ago I called the MD who I saw the first time and who prescribed Levaquin on 2/8, and told him the symptoms that the PA dismissed on 2/20 as a virus were all side effects of Levaquin. He actually had the stupidity to tell me that the pain in my joints and muscles was not a side effect of Levaquin, but the vertigo was. I replied that on the literature that came with the Levaquin it says that those pains are side effects. He is blatently lying to me to try to cover his and his incompetent, unskilled PA's asses!