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Suicide symptoms and conditions

Here are side effects posted by other members, that mention suicide.
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550 Side Effects posted for suicide

October 28th
2009
10:57 PM

My son is 7 yrs old with allergies and asthma. The Dr. prescribed it and the same day I had talked with a lady which her friends son just committed suicide. They were contributing it to Singular. A quick look up on the internet and I was angry with the pediatrician that the side effect was never discussed with me! After a very reassured conversation I said I would start him with 1/2 dose. I noticed nightmares started right away and I stopped. Asthma got worse decided to star again 3 weeks ago. He started twitching his head, flipping his hair that isn't even long. He was also complaining of stomach aches and not wanting to go to school (very unusual)! He has been off for a week now and is hopefully will not ever have any long term effect! Please follow your instincts and I will let his doctor. know what the side effects were.

-- By heatherabels | Reply | (2) replies | Private Message me

October 19th
2009
4:20 PM

I found this site 12 months after beginning Doxycycline for acne. A year ago I was the happiest person that I knew. I was a junior in high school and was very involved, liked sports, and had many friends. Me and my girlfriend were happy and to be honest, I had literally not felt happier.

A week ago I had come to the end of my rope. I literally decided to commit suicide. I finally reached out to God for help and I feel like he has saved me. About half an hour after praying for help from where I was I found this site. So, without further adieu, I am going to detail how horrific and absolutely from hell this drug is. ****PLEASE, I BEG YOU, IF YOU OR SOMEONE YOU KNOW HAS BEEN AFFECTED BY DEPRESSION, ANXIETY, OR ANY OTHER SIDE EFFECTS DUE TO THIS DRUG, PLEASE CALL THE FDA SIDE EFFECT HOTLINE. THIS DRUG IS FROM HELL***

I broke up with my girlfriend because I would sit at home and think for over 12 hours at a time that she hated me. As a result of this racing thoughts, when I saw her or went on a date, I would have nauseating anxiety for literally no reason... This anxiety continued for about a year until I had almost lost every friend I have ever had. It wasn't their fault, just that no one else knew how to respond to this sudden change in me.

Racing thoughts were terrible. I couldn't sit in a room without thinking thousands and thousands and thousands of negative thoughts from hell. I would think of how my family, and my friends, and my girlfriend all hated me. Now, after discontinuing this medication, i realize that it is all a lie.

The depression was horrific. I would literally have rather had a serious physical disease for the past year instead of feeling like this. I wouldn't go to parties, I would sit home and cry. Mind you, NOTHING happened to make me feel like this. Absolutely nothing. I thought about suicide about once a week (at least). I honestly didn't know what to do.

Mood swings were awful. I would change life goals and life core beliefs within minutes. Everyday I would become a different person at least 10 times throughout the day. I would go from nice, to sad, to motivated to start my own business, to thinking about signing my soul to Satan all in one day. These are just a few of the horrific thoughts. Dark thoughts, thoughts from hell.

I can report no physical side effects, but honestly I have been through so much that I can't stand it with this drug. I would like to thank my Lord and Savior Jesus Christ for helping me realize that this drug can absolutely ruin lives. I think everything happens for a reason, but people, hear me. I write with tears in my eyes right now and I look back on all of the lost time and all of the friends and all of the opportunities that have literally flown passed me. Just know that you are not alone. Stop taking this drug! And start raising awareness!

-- By andrewlca10 | Reply | (3) replies | Private Message me

September 15th
2009
11:12 AM

I am on day 5 of Loestrin 24, I do not read the "pamplets" that come with medicine simply because if I read it I will get it, power of suggestion is what my doc calls it. My boyfriend noticed almost immediately my mood swings, I thought I had the flu, I cry all the time and last night, after 4 days of no sleep I planned out my own suicide in my mind, even what I would write in the letter to my parents and my new niece. I layed beside my boyfriend and convinced myself he was cheating on me, he was seeing someone else and I got up, woke him up and started throwing his clothes in the backyard. I have full blown anxiety attacks and cry all the time. I am sick on my stomach but starving at the same time, my head is splitting wide open and I am waiting on a call rom my doctor right now. I called in to work "crazy" today, thank God my boss is very understanding and I will never take this pill again in my life. This is scary and as I sit here now I'm still not sure how long this feeling will last

-- By lilgreeneyedgirl | Reply | (2) replies | Private Message me

September 11th
2009
2:50 PM

My allergies caused nearly constant painful sinus pressure, drippy nose (I should have bought stock in Kleenex to profit from my box-a-day use), asthma, getting gradually worse all the time--it was as though I'd had the flu for 10 years (I'm 54). I was taking Claritin in the morning and Zyrtec at night, which only toned down the most severe symptoms. I was on Prilosec as well, as one doctor though acid-reflux might exacerbate the asthma. My family and I are avid hikers, but I haven't been able to breathe well enough to join them for years, even with daily Ventolin and Flovent. I've only been taking Singulair for two weeks, but it has made all the difference. I feel "normal" instead of sick for the first time in a long time. So, for me, it does work. But my stomach's been killing me--like a bleeding ulcer (which I had 25 years ago). I'm hoping that will subside or going back on Prilosec (expensive!) will counteract it. I've also had the weirdest dreams--very vivid and disturbing. Because I did research online before taking Singulair (Doctor uttered not one syllable about side effects), I recognize the dreams are from the Singulair. Because I understand what is causing them, I can easily set them aside when I wake up. I think anyone who's had mental or emotion problems could be sent over the edge by the dreams unless they had a clear understanding and acceptance that the allergy drug caused them. I would be easy to think something was wrong with you to dream such bizarre, violent stuff. (I'd give examples, but I've truly trained myself to forget all about the dreams as soon as I wake us, so I don't remember the dream events now.) I'm quite concerned about children taking this drug. Maybe not everyone has this disturbing-dream side effect, but how could you explain them away to a four-year old? How would you even know if a younger child was having them? Even children old enough to comprehend shouldn't be subjected to horrific mental images, like the 16 year old above. A tip for people who Singulair helps, but they have the weird dreams--try Melatonin (over-the-counter supplement) at bedtime. I've used it to help me sleep in the past when life events kept my mind too active to sleep for several days at a time. Unlike sleeping pills, it doesn't make your tired the next day, you can wake up easily, and it's not habit-forming--it just lets you drift off on days you otherwise can't. Since I'm concerned about the long-term effects of anything taken frequently, I don't take Melatonin very often, but I did try it after the fourth day of Singulair dreams. I had no memory of weird dreams when I woke up, so it seemed to work, and I didn't remember dreaming the next night either. I only tried it that one day because, as I said, I've trained myself to not be bothered by the dreams.

-- By singulair_helped | Reply | (1) replies | Private Message me

September 3th
2009
5:15 PM

My son's on 500mg. Depakote along w/Zyprexa for past 8 months. In past month he's had insomnia and doesn't want to go to sleep for fear of nightmares. He's dreaming he's going to die and someone's going to take him. Recently, i've read where Depakote can cause horrendous nightmares. what to do?

-- By cynkay2 | Reply | (1) replies | Private Message me

August 31th
2009
8:42 AM

I have taken hydrochlorothiazide for years and was told it was safe and worked well with blood pressure meds. I noticed that my weight gain would be 4 pounds on and off for no apparent reason. I also noticed my breasts felt like it did when I was nursing my babies when the milk came in. While on this med my potassium was off so I was on 3 fat potassium pills a day. Then I became light headed and became depressed and my mind was really awful. I knew I didn't have Alzheimer but knew something was wrong. Doctors thought I was a hypochondriac I am sure. I saw in Best Pills Worst Pills that you can have mental confusion as a side effect. I found out that when I went off of the pill for even a day the mental problems were gone and when I went back on the problems came back. After ingesting too much salt at a meal I ended up in ER. Doctor on call told me to quit my waterpill and also the potassium supplement, Since that time my weight has not fluated one ounce, my breasts no longer hurt and the mental chaos is gone. Such a relief to not have to worry where my potassium level was and never thought I would feel good mentally again as I was talking suicide. Meds they prescribe can kill us and we have to research all side effects ourselves it seems.

-- By dbaacke | Reply | Private Message me

August 28th
2009
8:48 AM

SINGULAIR'S LABEL HAS BEEN UPDATED:

The following has been added to the "Precautions" section of Singulair's label:

"Neuropsychiatric Events
Neuropsychiatric events have been reported in adult, adolescent, and pediatric patients taking SINGULAIR. Post-marketing reports with SINGULAIR use include agitation, aggressive behavior or hostility, anxiousness, depression, dream abnormalities, hallucinations, insomnia, irritability, restlessness, somnambulism, suicidal thinking and behavior (including suicide), and tremor. The clinical details of some post-marketing reports involving SINGULAIR appear consistent with a drug-induced effect.

Patients and prescribes should be alert for neuropsychiatric events. Patients should be instructed to notify their prescribe if these changes occur. Prescribes should carefully evaluate the risks and benefits of continuing treatment with SINGULAIR if such events occur (see ADVERSE REACTIONS, Post- Marketing Experience)."

-- By zsmom | Reply | (1) replies | Private Message me

August 19th
2009
7:48 AM

My 9 year old daughter got her first shot in Dec. 2008 and her second in Feb. and the last in June. We have have been to the doctor a lot of times due to headaches with the doctor's opinion being that it's "allergies". She is now on allergy shots with still no relief from the headaches. I listened to her pediatrician and got her the shots. I feel so bad now after reading all the problems others are having with this vaccine. She also has had a change in her attitude aggression,moodiness,cries often, and she says she's depressed. If anybody has any suggestions for us please let me know. I love my little girl and know I'm worried.

-- By hlo30 | Reply | (9) replies | Private Message me

August 17th
2009
11:14 PM

Our son, who is now 6 was prescribed Singulair at the age of 3 due to asthma/allergies. He was prescribed this by an ENT/Allergist. I thought our sons mood swings were due to the fact that we were expecting another child. He was always so happy/loving and playful. When the baby arrived 2 months later, his behavior worsened. Again, I put it on the new baby sister in the house. His moods/anger/outbursts increased. He hit, threw things etc. I told the doc about this and he said it was due to his enlarged tonsils, and they were then removed. Well needless to say, his behavior did not change because he was still on the Singulair. I mentioned the possible side effects to his pediatrician and she said it was a possibility, but to keep him on it because he needed it. Well, 3 years later, in March of this year I took him to an allergist that I had seen years ago. He immediately took him off the singulair (and all inhalers). His moods seemed to brighten a bit, but not they are worsening again. Is it possible for the Singulair to have long term damaging effects. I understand kids have tantrums, etc. Kids are kids, I get that. But he punches, kicks, screams, cries etc. My husband are at a loss. We don't know what to do. Oh, and he is now on Veramyst as needed (march-june, Aug-Oct.). Has anyone else experienced long term effects due to Singulair?

-- By onetwin | Reply | (1) replies | Private Message me

August 17th
2009
7:56 PM

I have never taken Levaquin but a friend of mine had a family member that was taking Levaquin when he committed suicide. He had taken about two or three doses of the 750 mg of Levaquin when he killed himself. We felt that Levaquin is the cause of him killing himself. He was not one that would ever think about killing himself. I seen him just seen him about 5 days before he died and he was doing great. He was his normal fun loving self. I personally will not take Levaquin. We did not know that Suicide was a side effect of Levaquin until after he died and someone told me about it. I look up the side effects and found Suicide and I told my friend. The doctors do not tell the patient that Levaquin has a side effect for Suicide when they write a proscription for it. I think that the doctors should warn people about the causes of Levaquin and let them decide if they want to take it.

-- By medgirl09 | Reply | Private Message me

August 2th
2009
10:51 AM

I am a 52 year old female and began taking 20mg. of lisinopril about 6 weeks ago. My blood pressure was very high 174/111. I feel terrible on this drug! I'm tired all the time, zero energy. I either can't sleep or sleep too much. I am a smoker but my coughing seems worse. I have a very dry mouth at night, I feel very depressed, crying a lot. Granted, I just lost my beloved nephew to suicide in May, but I can't shake the depression I feel. I am allergic to bee and wasp stings and was never asked this by the doctor. I'm going back next week and asking for a different medication

-- By susaninfl | Reply | Private Message me

July 28th
2009
6:21 PM

I've had numerous side effects from Synthroid, but the ones that finally scared me off the drug were the thoughts of death, dying and suicide.

These thoughts came as casually as thoughts of what I'll wear tomorrow, which was more frightening. They also came unbidden. First, I was thinking about death generally. About a month later, I began thinking about dying, and the whole process of dying. Then, when I started thinking about just walking in front of a train, I got on the Internet and did some research.

Synthroid was the only medication I take daily, so I stopped taking it at once. And about a week later, the thoughts of death, dying and suicide stopped. My doctor refuses to prescribe natural thyroid, so I'm out of luck until I find a doctor who will help me.

-- By kittywellington | Reply | (6) replies | Private Message me

July 25th
2009
10:13 PM

I am 45 and had the device inserted in June. Since then I have had an annoying constant red-brown discharge and my period three times. My menstrual cramps are definitely greatly lessened but what is freaking me out (apart from the discharge) is the anxiety I am experiencing for no reason. I am also feeling depressed. I am greatly concerned as being on the pill many years ago I had a mild stroke and my doctor assured me that the hormones ion the Mirena stay in the uterus. Why then the sudden anxiety attacks? I have always been a really laid-back person - I can only relate this sudden appearance of anxiety to the Mirena - it started about two weeks after I had it inserted.

I am now debating whether to ride it out - has anyone had the anxiety subside?

-- By katherineg2000 | Reply | (3) replies | Private Message me

July 22th
2009
10:12 AM

I am a 35 y.o mom of two and I had my Mirena put in Jan. 2008. I was patient for the first several months with some of the longer periods, cramping, etc. I was loving it initially since it was such low maintenance. But, let me tell you that since the Fall of 2008 I have had unbelievable emotional issues which have been far more severe than I have ever experienced. My two boys that are 5 and 6 and postpartum blues were nothing in comparison to this! I was recently married to my second husband in September and my emotional spiral got even worse during this time. By Feb. 2009, I was hospitalized a week for depression and attempted suicide. For a month after my discharge, I also attended daily outpatient treatment for which I was off work for the entire time. It has been a long road for me and my family and I'm still in therapy at least once a week and attend several support groups. Recently, I just started putting it all together because I have never experienced such emotional turmoil. I'm convinced it is related to the Mirena and I've got an appointment today to have it removed. I'm on so many medications now for my mood disorder that one more (birth control) won't be a big deal. I'm hoping that I will have relief of my symptoms once it is out. I empathize with everyone who has posted and it just confirms my suspicions.

-- By austinjake35 | Reply | Private Message me

July 12th
2009
12:53 AM

My eight year old son was diagnosed with mild asthma by our GP and was taking Ventolin for a persistent cough. When this didn't relieve the cough the doctor prescribed Singulair. He started the Singulair in March 2009 and within 2 months we realized that his personality had dramatically changed. It has taken us a while to figure out what was going on because eight year old boys are starting to assert themselves more and I think the side effects have been escalating over the last month. He was angry most of the time, very hateful towards his siblings, saying very dark, nasty, hurtful things. He argued every time we asked him to do something and would snap into a screaming inconsolable emotional wreck at the drop of a hat many times a day over trivial or imagined problems. He was having nightmares and bursts of hyperactivity that were overwhelming. He told us he felt frustrated all the time and hated everything. When we tried to calm him he was unreachable. Just yesterday he had his fist clenched and pulled back ready to punch me when I was trying to help him with a computer problem. He was shaking and his face was contorted with rage and he just wasn't my little boy anymore.
It has been devastating for our family and we were ready to take him to a psychologist. He is normally an incredibly considerate, perceptive, loving child, highly intelligent, helpful and fun loving with a great sense of humor.
He has also complained of leg pains and has been wetting the bed again. It was only yesterday that I began reading about other people's side effects and have taken him off Singulair as of last night. Whilst he has still been argumentative today already the aggressive intensity seems to be easing.
I am absolutely mortified that I allowed this to happen to my son and my family and I am so grateful to others for sharing their experiences.
We still need to address his asthma and will make an appointment with a specialist next week, but given his asthma is so mild he should not have ever had to suffer these side effects.
I only hope now that he has not sustained any long term effects and that his younger brother has not been scarred by the truly horrible things that my son has said to him.

-- By overwhelmed | Reply | (4) replies | Private Message me

July 6th
2009
6:25 PM

This drug should be taken off the market. My Dr. warned me of a cough when he gave it to me but did not tell me that you would literally drown in secretions from the drainage in your throat. I have been on it 2 weeks and my quality of life has diminished considerably. During the day its as if a little man with a squirt bottle of acid is spraying my throat. At night the same thing but lying down produces uncontrollable drainage. I have to keep a spit cup by my bed and hardly get any sleep. Have tried allergy medications to no avail. I threw it in the garbage today. I would rather monitor my BP 30 times a day than live thru this.

My question is if you have been on this drug and your Dr. took you off, what did he use in its place? Would Beta Blockers be better? Who has experienced this and is now free of it? What is the alternative drug? I called my Dr.'s office today and they have Benicar waiting for me in the AM...anyone know about that one? I am desperate!

-- By asbpiagentc | Reply | (2) replies | Private Message me

June 17th
2009
3:46 PM

I'm 15 years old and i've been taking prednisone for a few months, and from what i've read i'm on a really high dose. i was diagnosed with rheumatoid arthritis and another autoimmune disorder concerning my muscles at the same time. my doctor told me prednisone was my only choice; it was either that or i would lose the ability to walk. he told me there'd be side effects, but i had no idea it'd turn out like this or i would have fought harder for another course of action. i started out on 30mg twice a day, and since then was weaned down to 20mg twice a day and now i'm down to 30mg once a day. i've been looking up a bunch of information trying to figure out if there's a way to lessen the side effects or any hope at all that they will get better. apparently there isn't much. after reading a bunch of these stories i gotta say i'm not feeling great about this. i totally understand everything everyone is going through. i'm sure you can imagine what it's like being smack in the middle of high school with a huge puffy face, acne so bad on my face, chest, back, neck, and shoulders that wearing a bra could put me in tears, and mood swings so bad i've lost friends over it. everyone knows how brutal high school can be, where appearance and attitude are everything. and i try to tell my doctor about it and he literally looks at me like i'm a whiny teenager and says "you're just going to have to deal with it." and people like my mom and my closest friends don't get it either. nobody understands how beyond frustrating it is. i'll get into the worst moods and not have a reason for it, but i'll stay angry for hours or burst into tears over someone looking at me the wrong way. it'll get to the point where i have to isolate myself from other people because the abrubt mood changes get so bad. as bad as i hate to admit it, the pain from the arthritis is gone now and supposedly my muscles are doing better too. developing arthritis caused me to have to quit cheerleading, something i've loved doing for 6 years, because the pain got to the point where i couldn't get my arms above my head or bend my knees. however, i'd almost rather deal with the horrible joint pain than deal with the side effects of prednisone. if your doctor gives you and alternative method, take it. i've always been confident in the way i look and really outgoing and happy and now i sometimes catch myself thinking about suicide. that's shocking to me because i've got so much going for me, but this medicine makes me miserable. and when i complain about it, anyone i'm talking to just looks at me like i'm being a cry baby. my mom does too, she'll say things like "you just have to do this. i know it's not what you want but to be honest i'm sick of hearing you bitch about it."
i feel a little better knowing other people feel the same way - like nobody gets whats going on with them. the prednisone does give me days of really great euphoria and days when i feel like i could run a marathon, but waking up in the morning to the acne and huge face puts me to tears every day. i have to pee all the time, usually getting up at 2 or 3 am. i don't sleep well anymore and i do sweat all the time. which also sucks being a teenage girl. i'm always hungry, and when i eat i never feel full so i don't know when to stop. my neck and face have put on so much weight that when people see me in the halls or out and about they ask me what happened. mind you these are people i don't talk to, just ones i know from classes or whatever. and it's pretty bad when teenage boys i've never really talked to ask what happened to your face. kind of a blow to the ego, or whatever is left of it at this point.
i'd like to know if, as my dosage gets lowered, the side effects will diminish and when i'm off the prednisone completely if they will disappear altogether. any help there?
or if there is any way to help the acne or puffy face

my doctor just put me on something called methotrexate or something like that to help wean me off the prednisone, and does anyone know what those side effects will do? or if they'll affect the prednisone side effects?
i'm constantly obsessing over gaining weight and what my skin looks like and what i eat and how heavy my face feels and the occasional pressure in my eyes to the point where i just want to be put out of my misery.
and after reading other people's stories i really don't understand why this drug is still given out as freely as it is. but maybe all doctors are like mine, they just don't get it.
best of luck to anyone who's on prednisone, my heart goes out to you; i'm right there with you
sorry this became like a book it wasn't meant to be this long

-- By db1993 | Reply | (12) replies | Private Message me

June 17th
2009
2:10 AM

Ladies,

I hope you don’t mind a male posting on this forum but I do have a reason for doing so. I am a Coroner’s Officer in England. I will not at this time disclose whereexactly I am based as I need to protect the identity of the family. I would however like to use you as a sounding board in the hope that you can help me, help the family and perhaps, just perhaps, I can help you.

Sadly I am dealing with a suicide. The lady in question, who has taken her own life is in her 40’s, married and has children (all over 11 years). The lady has no history what so ever of any form of depression during her life.

The lady has described her life as being perfect with a family that loves her and who she loves in return and as the Investigator I believe she is truthful in that comment. She states she has been extremely happy until last week. She makes comments of - I am just very ill, cannot sleep, feel dizzy, cannot concentrate, sometimes lose my vision, feel sick all the time and sweat at night. She cannot understand, but it makes her feel bad. I am not myself, something has made me ill which means I can’t be my normal positive, active busy self. I can’t bring myself to do anything that I normally love, like gardening, cooking etc. I am losing my memory badly going fuzzy in the head.

Her final comment, which is the one that has prompted me to post on this forum (with the permission of the family) is ‘I just don’t understand this – I’m so sorry . I can’t understand myself or what is wrong with me or what I’m doing so sorry. Just remember I’m not myself somebody else has taken over – I don’t know if it is all the anti-histamine pills that has mixed up my chemical balance along with the Mirena coil or is it just me’.

The mention of the Mirena coil has therefore prompted me to investigate it. I am not, by any means suggesting that this is responsible but it would be wrong of me to discount it after having read the posts on this forum and other places on the Internet.

The lady in question had the coil inserted in 2004/5 and it would appear that there were no problems or side effects reported.

I am therefore looking for some help from you. Some comments on what I have posted etc. Some advice on where to obtain expert advice (although I am trying some avenues of my own).

I may also ask, depending on what help you can give me if you would be willing to identify yourself to me.

Thank you

P.

-- By paulhmco | Reply | (6) replies | Private Message me

June 16th
2009
6:03 PM

My 13 year old daughter has been taking singulair for 8 months, and started suffering from severe depression 6 months ago. We intervened and prevented her from committing suicide, but barely. We never correlated it with the Singulair until a visit with her pediatrician today. I am so sad I want to cry. I am the one that suggested to her asthma specialist that she be put on Singulair. I am so fortunate her pediatrician caught this. We couldn't figure out why her personality suddenly changed.

-- By mmmc2 | Reply | (2) replies | Private Message me

June 13th
2009
1:06 PM

As i read some of the news reports on the new FDA comments,i see we are referred to as a handful of reports,the very words handful conjure up a picture of 10 not the thousands that there actually are.Also i noted missing from the news reports was ,that this drug is largely given to children,as young as 6 months,not for 10 days or 2 weeks but everyday,for as long as they need it.i know myself trying to convince my doctor,that my sons depression,insomnia and anxiety,came from this drug was impossible,so i fired him.I am wishing the best to everyone that has suffered,and ask all to please report your adverse effects to the FDA

-- By flindy | Reply | (1) replies | Private Message me

June 13th
2009
9:19 AM

PLEASE REPORT SIDE EFFECTS OF SINGULAIR TO THE FDA: https://www.accessdata.fda.gov/scripts/medwatch/medwatch-online.htm.

The FDA is continuing to monitor ongoing reports of suicide and other psychiatric problems.

-- By zsmom | Reply | (1) replies | Private Message me

June 12th
2009
8:16 PM

From the FDA's "Updated Information on Leukotriene Inhibitors: Montelukast (marketed as Singulair), Zafirlukast (marketed as Accolate), and Zileuton (marketed as Zyflo and Zyflo CR)"

6/12/2009

Neuropsychiatric events have been reported in some patients taking montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo and Zyflo CR). FDA has requested that manufacturers include a precaution in the drug prescribing information (drug labeling).

Montelukast is used to treat asthma, and the symptoms of allergic rhinitis (sneezing, stuffy nose, runny nose, itching of the nose), and to prevent exercise-induced asthma. Zafirlukast and zileuton are used to treat asthma.

The reported neuropsychiatric events include postmarket cases of agitation, aggression, anxiousness, dream abnormalities and hallucinations, depression, insomnia, irritability, restlessness, suicidal thinking and behavior (including suicide), and tremor.

This information reflects FDA’s current analysis of available data concerning this drug.

Advice to patients and healthcare professionals:

Patients and healthcare professionals should be aware of the potential for neuropsychiatric events with these medications.

Patients should talk with their healthcare providers if these events occur.

Healthcare professionals should consider discontinuing these medications if patients develop neuropsychiatric symptoms.

Background

In April 2009, FDA completed its review of neuropsychiatric events, (mood and behavioral changes) possibly related to drugs that act through the leukotriene pathway (montelukast, zafirlukast, zileuton). As part of its review, FDA reviewed post-marketing reports and also requested that manufacturers submit all available clinical trial data for these products.

The post-market reports of patients on these medications included cases of neuropsychiatric events. Some reports included clinical details consistent with a drug-induced effect. In the clinical trial data submitted by manufacturers, neuropsychiatric events were not commonly observed. However, the available data were limited because the trials were not designed to look for neuropsychiatric events. Sleep disorders (primarily insomnia) were reported more frequently with all three products compared to placebo.

view replies for more information

-- By zsmom | Reply | (8) replies | Private Message me

June 8th
2009
12:18 PM

ok, so I am 28yrs old just had my second lap for endo and my doctor has recommended lupron, after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do, my post-op surgery appt is this week, and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

-- By lnbinion | Reply | (12) replies | Private Message me

June 1th
2009
11:17 PM

I've been on lipitor and other generic forms of it for the last 8 years since the age of 26. I started on 10mg then 20mg and later 40mg. About 4 years ago I started with severe stomach cramps. The pain is so bad that I have to go home in the middle of the day, I can't walk or sit straight the pain is that bad and NOTHING helps. On a scale of 1 to 10 I would probably put this at a 7 or 8. I would also be nauseous and be really tired. I have had countless opinions and tests done and doctors keep telling me it is an "enigma" and there's nothing wrong with me. We've treated it through coeliac diet, exercise, lots of water, but it never helped. About a week ago I stopped drinking my meds by pure chance. I have not had one incidence of stomach ache. My doctor tells me that it's not possible for the lipitor to be the cause. I am sure he's wrong. Has anyone had a similar experience?

-- By nans | Reply | (7) replies | Private Message me

May 19th
2009
11:27 AM

I took Singulair for about two years. I had developed these now known to be side effects but at the time nobody including the FDA was either aware or honest about the aggression, agitation and other side effects. I assumed this was all due to stress in my life and since it came on so gradually I did not put 2 and 2 together that it was the medication. I lived for two years being an irritable stressed out pain in the you know what struggling with these major aggressive compulsions. Then I saw a story on the news that the FDA was issuing this new warning on Singulair about the aggressive, anxiety and suicidal side effects of this drug. I stopped taking it that day. Luckily my asthma had been fairly well under control, I noticed no increase in asthma symptoms. What I did notice was I stopped being irritable and constantly annoyed and angry within a few days. I am back to being a mellow person, no problems since I quit this drug. I am horrified they are giving this to children. Both doctors and pharmacists should be warning people UP FRONT of this risk.

-- By lucillefarh | Reply | (2) replies | Private Message me


 

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