Swollen ankles and feet symptoms and conditions

I have been using Topamax now for 8 years off and on. I stopped the Topamax about 3 months ago, something I do once or twice a year to try and feel 'normal' again. Then last month I went to see my regular doctor because of numb, pale, swollen, achy fingers, swollen ankles and feet, and for a papercut on my knuckle that overnight turned into a radical staph infection. The NP ordered a full blood panel and the results came back positive for Lupus. I have had so much pain in my hips and knees, more frequent headaches (not migraines), insomnia and vision trouble. The past two weeks I have been super irritable and nauseous. I still need to have a 2nd opinion and/or referral to a rheumatologist, but is all of this related to taking the Topamax? I take 2 Imitrex injections if a migraine comes on and am hesitant to start the Topamax if it has indeed induced Lupus. Am I crazy or is this common??? THANKS for the feedback...SM.

I have had thyroid disease for 6 years. I just had my medicine increase less than one week ago from 125 mcg to 150 mcg. The endocrinologist did this with a lab result from over 6 months ago and I was never retested before he upped my dose. 2 days after my new dose I broke out in a rash head to toe. The next day I started itching and went to my doctor and she said I have no idea what is going on with you. Then I went to the Pharmasist and he said you are having an allergic reaction to the dye in the 150 mcg blue tablets (125 mcg are white). The following day I got new medication I now am taking 3 50 mcg tablets. But I now am swollen ankles to feet and elbows to hands. My hands are like balloons. When I go to bed at night my hands are completely numb. Has anyone else had any symptoms like this?? Help I cannot figure this out. I am thinking that I may be over medicated. Thank you Heidi