Tendon ruptures symptoms and conditions

You really need to be extra-aware of the possibility of tendon damage. There have been a lot of reports on these side Levaquin. A lot of people have developed serious tendon injuries including tendon ruptures and severe tendinitis. Take a look at ****** -- there's lots of literature and studies showing that many takers of fluoroquinolones have suffered terrible side effects after just single uses. You need to be aware of this so you can take action (like getting to a doctor) before major damage sets in. Hope this helps.

You really need to be able to recognize the onset of tendon injuries. As you can see on the board here, thousands have developed serious tendon injuries including tendon ruptures and severe tendinitis. Take a look at ****** -- there's lots of literature and studies showing that many takers of fluoroquinolones have suffered terrible side effects after just single uses. Let's get out the word so doctors and patients are fully aware before undertaking the risk fluoroquinolines pose. People need to be aware of this so they are able to take action (like getting to a doctor) before major damage sets in. Hope this helps.

My son (14 years old) was given levaquin for a sinus and ear infection
2 weeks ago. Around the same time he began practices for his high school baseball team. He complained about his legs being stiff and aching. We assumed it was the intense practices causing his muscles to ache. After a week on the drug, he could barely walk and his knees were swollen. We were very concerned and looked up the side effects of levaquin on the internet. We were shocked and angry when we found out that levaquin should not be given to children under the age of 18 because on the possibility of joint and tendon problems. Today we went to the orthopedist and he drained a lot of fluid off of both knees (it looked like about a 1/2 cup from each).The doctor thinks it has to be a side effect of the drug, because the symptoms began at the same time. He doesn't
think after examining the knee and having him perform certain tasks that he has damaged any tendons. He has all the symptoms of rheumatiod arthritis. He is very athletic and plays competitive sports and we are praying that his knees are not permanently damaged by this drug. Parents please research all drugs and there side effects before giving them to your children! Doctor's DO make mistakes!! The pharmacist failed us too.

had a moderate to severe reaction to levaquin 2 years ago.. we know the symptoms.. Here is what i did to help.
1) Eat only ORGANIC They spray meat that isn't organic with floxins, do NOT eat processed foods, fast foods, start cooking at home and eating RAW You wont believe how much better you will feel when you go organic. Vegetarian and Vegan even better. ALKALIZE get your PH to 7.5. Acidity is the worst when you are sick like this
2) Hulda Clark cleanses...Dental Kidney, Liver , Parasite , Bowel ( *******)
3) Keep moving
4) i used some stuff called waiora its amazing
5) sun, swim in ocean if you can and walk an hour a day 5) be positive 6) JUICES buy a juicer and drink a beet, cucumber, lemon , ( ORGANIC!!!!!) with one tablespoon of organic olive oil, drink every day
7) fish oil, calcium and magnesium , a good pure multivitamin ( crainuls on *****)
8)Don't be obsessed with whats wrong, get into what feels better.

Now I know why I've felt so bad. I got a sinus infection that was so bad my teeth hurt. My ENT prescribed AVELOX and prednisone. After a week of feeling like crap (much worse than the symptoms that took me to the MD in the first place) I now know why I feel as bad as I do - I owe a big apology to prednisone, I've been throwing it under the bus all week.

I'll be calling my ENT shortly.

1) Stop going to the doctor for "sinus infections". This is one of the most over diagnosed, over treated, self-limiting illnesses in the world. Because 90% is viral, it's also the leading cause of antibiotic resistant bacteria in out-patient medicine. Get some Afrin and blow your nose.
2) Avoid taking fluoroquinolones (Cipro, Levaquin, Avelox) as an outpatient. These powerful drugs should be used to save lives in the hospital. The leading exception would be a urinary tract infection that is resistant to all other antibiotics.
3) All fluoroquinolones can cause tendon ruptures, especially the achille's tendon in patients over 65. This is a devastating injury, though rare with this class of antibiotics.

I took Levaquin 750 for 10 days for a sinus infection. I took first 5 doses, went to see my doctor again 6 days later because I was still sick. She prescribed again 5 does of Levanquin 750. I am still coughing and I feel very tired. It did not help at all. I am still sick and I have muscle pains in my two calves and stress Achille tendon. I am a runner and I have sometimes problems with my calf: I have been not running too much recently and I was wondering how come suddenly I had those muscle pains in both my calves. I am not sure if it is related to Levaquin, but when I read all those comments, I am worried. Why I have been prescribed this antibiotics if it is obviously dangerous?

I am 35 and I took Levaquin about 3 months ago when I experienced pain in my hands and achilles tendon. Fortunately I figured out what was going on before I had a rupture. In an effort to repair the damage one of the things I did was take a few joint and tendon supplements. I took Ligaplex I, Super Cissus RX, Fish Oil, Glucosamin, Condroitin, and MSN. I believe these supplements where a big help in my recovery. If you are going to use these supplements make sure you take them as directed because each has it's own recommended schedule.

Update on my post of Aug. 11th. I did see a neurologist who was a bit skeptical, but after looking it up did acknowledge that this drug can cause tendon ruptures, etc. Later that week he did a nerve conduction study, both the one with the needles and the one where they shock the muscles. He was happy to report that I did not have any "nerve" damage. I had already told him that I did not think I had neuropathy as the numbness had gone away and was just replaced by the constant pain in my joints, etc. I then went to see my rheumatologist who was also just as skeptical that the drug could be causing all the pain I was describing. She said she had had three patients with tendon ruptures, but nothing else. I really don't care what she believes, and I told her so. I know what happened and what horrible pain I have been in ever since. I hate to report that the pain in my feet, knees, hands, hips, back and now my neck are not any better. My insomnia is some better, but I am taking more Lyrica. I tried a different antibiotic yesterday for the sinus infection called Clindamycin. OMG! I took one pill and within a few minutes had unbelievable heartburn. That lasted for 12 hours, along with reflux, burping, weird stomach noises. Now, I can't take that. Doctor called in a prescription for Augmentin this morning. Afraid to try anything now, but guess I will give it a shot. Is anyone getting any better from their joint or muscle pain? Some encourgement would be good. Thanks.

I was a healthy 42 year old male who took Levaquin for a sinus infection. The same day as the Black Box Warning was issued; I was having my third tendon reattachment surgery. I have to wait at least 6 weeks before I can undergo yet a fourth tendon rupture reattachment. At least it takes my mind of the Achilles Tendinopathy, joint pains, headaches, uncontrolled muscle twitching etc. I consider myself one of the lucky ones since so far it has not affected my kidneys, liver, heart, eyes and other side effects that many are dealing with from this class of drugs. I would urge a real journalist to take the time and look at the real number of cases. The Fda numbers are misleading. The clinical data coming from other counties are showing much higher rates of tendon ruptures and other life threatening side effects.

I did not think I had an adverse effect from Levaquin until I read that it can cause tendon ruptures. I had a year long experience including extensive
surgery from a torn tibialis tendon. I did not take Levaquin unitil I had a slight tear that resulted in a full rupture, tendon transplant, heel breaking and arch rebuilding.
I had taken Levaquin after I was put in cast to try to heal my tendon, which never happened. Could Levaquin have had something to do with this.
My problem with my foot happened in 12/06 and my first dose was during the month of January 2007. After I had recouped in November of 07 I also took levaquin in March of 08.
Please let em know if this could have had an adverse effect on my situation
and what I could do about this.

Saw this story on CNN today. Guess we aren't all tinfoil-hat wearing nutcases after all.

******

FDA orders 'black box' label on some antibiotics

The U.S. Food and Drug Administration Tuesday ordered the makers of certain antibiotics to add a "black box" label warning -- the FDA's strongest -- to alert patients of possible tendon ruptures and tendinitis.
Cipro is one of the drugs for which the FDA will require a "black box" label warning about tendon problems.

Cipro is one of the drugs for which the FDA will require a "black box" label warning about tendon problems.

"The new language will strengthen the existing warnings," said Dr. Edward Cox, director of the FDA's Office of Antimicrobial Products.

The FDA is requiring the label warnings and a medication guide for fluoroquinolone drugs, which include Cipro, Levaquin, Avelox, Noroxin and Floxin.

The consumer group Public Citizen asked the FDA in August 2006 to put the "black box" warning on Cipro and other fluoroquinolones, and also to warn doctors. Earlier this year, Public Citizen filed a lawsuit to force the FDA to take those actions.

When asked about the lawsuit and why it took so long to add the label warning, Cox stressed that the FDA included warning information with the drugs from 2001 until 2004, and updated the information last year.

"There has been ongoing work to update the labeling of the fluoroquinolone drug products," Cox said. "We have been working on this issue and making progress over time."

The companies that make the fluoroquinolone drugs will be required to submit label safety changes and the medication guide within 30 days of receiving the notification from the FDA or provide a reason why they do not believe such labeling changes are necessary, Cox said.

The fluoroquinolones drugs can increase the risk of tendinitis and tendon rupture -- which is about 1 in 100,000 -- by three to four times, according to the FDA's Dr. Renata Albrecht.

"This risk is further increased in those over age 60, in kidney, heart, and lung transplant recipients, and with use of concomitant steroid therapy," the FDA said in a statement.

Albrecht said that sometimes patients have no symptoms before they experience a rupture in their tendon -- commonly their Achilles tendon.

"Sometimes it's been reported on the first day of taking a fluoroquinolone ... a sudden snap or popping sound that is tendon rupture with no preceding warning," she said.

Normally, she added, that patients experience some pain or inflammation "a week or two before the patient will rupture."

The FDA would only say that it has received "hundreds" of reports of tendon problems linked to fluoroquinolones, without being more specific, citing the ongoing lawsuit. But Cox said "the FDA continues to receive a considerable number of reports on tendon adverse effects."

Patients should stop taking fluoroquinolone antibiotics at the first sign of tendon pain, avoid exercise and contact their doctor, the FDA said.

Cox said the FDA would not require companies to send letters to doctors alerting them about the connection between tendon problems and the antibiotics.

"It is possible under REMS to ask for a letter ," Cox said. "Certainly for sponsors that would choose to go forward with a letter, we'll be happy to work with them."

Most of the "side effects" are die off responses (sometimes referred to as a herxheimer response similar to that which occurs when treating syphillis) from bartonella or borrelia. Levaquin is a potent intracellular antibiotic...where these and other organisms can hide. These can be subclinical infections where (at this time) you are not even aware you are infected. If your "side effects" start around the 3rd day into your prescription...rejoice...and suffer for a while, you are killing something really bad.

PLEASE READ:

I have posted my side effects here before. Was floxed at least twice but didn't put 2 and 2 together because the side effects came well after I had taken the medication. I caught it this time because I was on a higher dose. I was on Leva-Pac 750mg for 9 days. I have had 2 distal bicep tendon ruptures and surgery each time.

It's nuts that there is no treatment for the person who is floxed and how many doctors and hospitals are telling us this is all in our head. This needs some coverage. I had thought about Sonja Gupta on CNN but every other commercial is from a drug company.

Then I thought of Helmet Oz on Oprah. He is into alternative medicine and if he did a segment on Oprah I think it would raise awareness. I am writing and urging you to do the same. I am telling him my story and the lawsuit that Public Citizen with the Office of the Illinois Attorney General against the FDA to blackbox this medication.

Please follow my suit and submit a letter and also spread the word to other floxed web sites. The link to Oprah is
http://www.oprah.com/email/reach/email_showideas.jhtml

Crapshot, thanks for the info on your thoughts. But in my case as well as others I do not believe this is at all related to Candidiasis. If you scroll down and read my post you will see that I have snapped two biceps from Levaquin. This in not the first time I was Floxed But the other times I was on lower doses and the symptoms didn't appear until well after I had finished my prescriptions. Not only did I have to have 2 surgeries but I was also having heart palpations and severe joint pain that went away after months of my body cleansing itself. This time I figured it out because they put me on a higher dose for a longer period. This time around the symptoms started before I finished my course. I quit taking the Leva-pak and googled the side effects. And they were spot on. Not only do I take probiotics and vitamins daily but I work out and do cardio 4 to 5 times a week, and eat a healthy diet. At the ripe ol age of 41 the doctors were amazed that I have torn each bicep tendon from the bone in a 2 year time period. I AM blaming the pill. Also Public Citizen along with the Attorney General from Illinois is suing the FDA to get this Black Boxed. They are also suing the FDA because they haven't been updating the newer cases of tendon ruptures. It's easy to blame the consumer, but do you think I would have taken this after my history with this medication. If they had the proper warnings and black boxed the tendon rupture I wouldn't have even allowed this drug to be in my house. I'm glad you didn't come away with the serious side effects but please don't blame the patients.

Levaquin actually worked great when I took it. I was diagnosed with epididymitis after a urine culture was analyzed and the doc gave me a 10 day supply of Levaquin to take once a day. The side effects I felt were pain in the abdominal area, headaches, anxiety, confusion, and dizziness. Those I could live with, because the epididymitis problem had more side effects than the drug. The trade off was worth it. I'm on my 7th day of Levaquin and I feel a whole lot better than without it. But do beware some people do react badly to the Levaquin family of drugs including cipro. This is some powerful stuff not to be messed around with, it is also used to treat HIV patients and people who had post inhalation of Anthrax. Yes it is powerful enough to treat those dangerous conditions. When you take Levaquin just get plenty of rest drink lots of water AND Cranberry juice which prevents unitary tract infections. Do not exercise while on this medicine for it will cause tendon damage, just take it easy for the whole time you are on it with plenty of fluids. Get better and stay healthy.

Hey you all......the lipitor saga continues. I posted #23428 on Sept 6th. On Sept 13th I picked a 30 pound piece of fabric up at work and there was a big POP in my left arm. Distal Biceps Tendon rupture.....TORE it off the Bone. I have been weightlifting for 20 years and never had an injury such as this. I am used to lifting much heavier weights with no problem. Had surgery to reattach 9/18...7 weeks post op and still in brace. Will take a year to fully heal. Both my doctor and Ortho said they have never heard of tendon rupture caused by statin drugs...but I am convinced that it was directly related to lipitor damage/side effects. I did have my doctor shaking in his shoes, I told him with conviction that I would never again take a statin drug and I held him responsible. Would like to hear from anyone who may have had tendon issues while taking this drug. I hope we all get better soon!
Peace
Brian

I was prescribed the levaquin for a sinus infection. I developed severe muscle aches and pain in both legs and especially my feet, such that it was very painful to walk. Also, my joints felt sore and swollen all over my body; even my neck hurt. My physician said to stop the levaquin right away. I heard that others have had this problem and that there are possible spontaneous tendon ruptures. But I also heard that these symptoms go away... mine have not, and it has been over a year now. It's very painful. Very painful, indeed. I can't say that it was worth it to take the levaquin, as I was then prescribed another antibiotic which took care of the problem without these side effects. I wish I had never taken it now. I also have edema to the lower extremities now, but I don't know if that also is from the levaquin. Hard to say. My physician told me that my aches, pains, and swelling are not from the levaquin, otherwise those symptoms would have gone away after stopping the drug. No one seems to be able to figure it all out. Lab tests so far are negative for gout. Go figure.

I took Levaquin several years ago for pneumonia after being misdiagnosed and treated for bronchitis. Within three days, my breathing improved but my body felt worse. By the third day, I started having what I thought was joint pain in odd places: feet, ankles, knees, wrists, fingers, elbows and shoulders. I called the doctor who told me not to worry, that these were side effects that would go away. I kept taking it because I was desperate to get well after months of being sick and misdiagnosed, but the side effects worsened. I called again and got the same advice. By Day 13 and in tears, I started researching it and found a website that detailed the horrible side effects that people were experiencing, how the drug was implicated in bilateral tendon ruptures, how Nader's group had petitioned for warning labels detailing these dangerous side effects and been denied, and how the symptoms persisted in some for years.

By the time I stopped taking the drug (Day 13), I could not lift my right arm over my head, a symptom that persisted for about six months. I immeditaely went to see a rheumatologist who told me it was not my joints but my tendons that had been 'attacked' and that I should have stopped the drug immediately at the first sign of a problem. He said that over time I would improve.

What disturbs me is that my experience happened FOUR YEARS AGO and there were many who had similar experiences who preceded me by several years. That this situation still persists in unconscionable.

The side effects lasted for several years but the varied. At one point, every time I kneeled I felt there were rubber bands across the front of my knees that were about to snap. For a while, my ankles were very weak, etc.

I would say that it took about 3 1/2 years to be rid of the symptoms so it may take that long and longer for some to detox from this dangerous drug.

Hope that helps.

Susan

Though I have posted this information a couple of dozen times on this site I am posting it again for the benefit of the new victims. Fluoroquinolones, to which levaquin is but one such drug, has been associated with IRREVERSIBLE PERIPHERIAL NUEROPATHY, SPONTANEOUS TENDON RUPTURES, HEART ATTACKS, STROKES, Liver and Kidney damage, vision and hearing damage and about 14 pages worth of serious and non abating adverse reactions. If you are experiencing unusual symptoms while on this drug chances are very good that you are having one of these reactions. Please report your experiences to MedWatch as well as your physician and if at all possible try to have him or her change your medication to a safer alternative. Fluoroquinolones are a drug of LAST RESORT and are NOT to be used as a first line agent. For further information regarding the adverse drug reactions associated with this toxic chemotherapuetic agent log unto www.fqresearch.org or if you prefer to hear others described their living hell after being on these drugs check out the quinolone adverse drug reaction forum hosted by Yahoo. Currently there are over 1200 victims registered at that forum. As well as www.fqvictims.org which also has detailed reports from others whose lives have been destroyed by the careless scripting of these drugs from hell.

Im a 39 year old male in good health, diagonosed 2 days ago with Epydidimitus of my right testicle, possibly bacterial. My GP prescribed a 4 day dosage of Levaquin after giving me 3 sample 500mg tablets, told me to keep out of the sun and to call him if there were any reactions like a rash/sunburn. When I enquired as to whether I could continue my daily 2 mile bike rides, he suggested I not and I concluded it was due to the Epydidimitus. There was no insert in the sample packs, I filled the prescripton and would pick it up later that day.
However, at work I proceeded to do an Google search on Levaquin at Ortho-McNeil and was alarmed at what I read. I found this site and concluded that I didn't want to take fluroquionones for my illness and now understood why bike riding wasn't a good idea (possibility of Tendon Ruptures!!!).
I called my GP's office, spoke with the nurse and requested an alternate antibiotic. I was told the GP would be get back to me. The next morning his nurse called and instructed me to either take the Levaquin or see the in-plan urologist. An co-worker told me he'd requested not to receive Levaquin for a UTI, as it gave him leg cramps after he'd stopped taking it. I called a drug-rep friend of mine, inquired about Levaquin, was told it was being given out "like candy", most widely prescribed AB, safe, he's taken it, etc. But he'd also seen side effects and was surprised my GP wouldn't prescribe an alternative. He put me in touch with a PA at my urologists office, who called me back within an hour. The PA agreed that it was reasonable to prescribe something less powerful, as fluoroquinones are usually 2nd or 3rd line drugs. He agreed to see me the same day. I then called my GP's office to request that he get on the phone for 5 minutes at his convenience to discuss an alternative drug, but only received a call back from the head nurse who would relay the message!?? The PA did an exam, explained that quionones are often prescribed at his office after a patient hasn't responed to other antibiotics prescribed by a GP. His prognosis was the same as my GP, however he also suggested I get an ultrasound in addition, just to be sure.
End result, I was prescribed Doxycycline 100mg/2xDay for 14 days and will follow up in 3 weeks.

DON'T GIVE IN WITHOUT A FIGHT! If these drugs are unsafe, and there is even a 1% chance of major complications (Levaquin 46% of all patients reported adverse effects of some sort), why take them unless absolutely necessary! This is a family of drugs, that while being very powerful, was originally approved as a 2nd or 3rd line of defence, when other AB's didn't work. GP's may be prescribing them as wide-spectrum cure-alls without knowing the frequency of adverse side-effects. They already work 10+ hour days, why would they hop online to investigate negative effects reported to non-profit watchdog sites? We're not doctors, so what do we know...right? WRONG! Do your homework, ask questions, be considerate but firm. You have the right to ask for alternative treatments so long as you are informed. God Bless, best wishes.

Oops! Excuse the entry below. I goofed & hit the wrong key.
Anyhoo, here is my Levaquin story. I am 51 & was diagnosed with cellulitis on Jan. 19th of this year. I was given an IV drug, (Daptomyacin) & 500 mg of Levaquin for 16 days. Towards the end of the treatment, my joints became very achy. (mostly in my knees) I was having burning, tingling sesations throughout my body & my calves were cramping. One week after treatment, I could barely walk through our house. I normally am active, with daily walks & short jogs. Within days, I had to have knee surgery. It is now almost 5 weeks past my surgery. The achy joints, burning, cramping & tingling are still present off & on throughout my body. Although the orthopaedic surgeon did find trauma in my knee, (past fractures, etc.) I am convinced the Levaquin sped up & exacerbated the damage. Now my other knee is hurting so bad, I am starting to think that one will need surgery as well. Both my orthopaedic surgeon the infectious disease Dr. that prescribed the Levaquin dismiss the notion that Levaquin had anything to do with it or that my joints are aching because of the drug. I am thrilled I find this site, because I realize that I haven't imagined these symptoms. But the reality of these reactions is quite sobering. I have never had a bad reaction to a drug in my lifetime. This one was so sudden & severe, I had to add my account to this list. I've just started trying the Milk of Magnesia & hope it works. I too have been drinking lots of water. God bless each of you out there suffering with this & may we find some solutions soon.