Tip of the iceberg symptoms and conditions

I have been on Lantus & Humalog for about 3 years. I am a 75 yr old male T2 and the only other meds I currently take are Toprol XL and aspirin. After reading all these Lantus postings, I decided it was time to quit Lantus just to see what happened. Like one other person said, "all of a sudden the fog lifted"! I am a different person. I can now sing in church (after 3 days off of Lantus). Before this, I did not have enough breath to sing. When I was on Lantus I had many sleepless nights, suffering from RLS and leg pain. Now I am sleeping the entire night through. These benefits are the tip of the iceberg, I just feel better all over. Needless to say, I am injecting more Humalog now to make up for the absent Lantus but that will not be a problem. Please understand I am not advocating this for anyone else, I am simply reporting what happened to me. I see my doctor in a couple of weeks and can't wait to share the news with her.

I have been prescribed cipro 2x for diverticulitis and has adverse reactions (after completing the recommended prescription) to dairy and fruits (citrus acid). When another bout of diverticulitis occurred, I asked my doctor not to give me cipro. He does some research and prescribes levaquin. I completed the prescription and now more than ever have adverse reactions to dairy and fruits and anything that has whey or citric acid in it. I think this is just the tip of the iceberg of exactly what I am allergic to. I have done extensive research of the adverse reactions from cipro and levaquin which for me once I eat these particular foods is extreme case of hives and skin rash. I have to take benydral. Sometimes it helps and sometimes it does not. I went to my gastroenterologist and allergist with complaints from taking these drugs and they have told me they have never had anyone come to them with complaints. Who are we kidding? With all the reading I have done, these drugs are poison. Although I know I am among the extreme side effect category, I need help and I can't get it anywhere. I have also read that these quinolone antibiotics are given to the animals, foul and fish that we eat. So does that mean we are ingesting extra quinolone into our systems when all we want to do is have it wear off? My wife feels that we should eat organic meats. I tried organic milk and I have reacted to it. I just want a bowl of cereal and a normal cup of coffee. Whey also gives me hives. Whey is in almost everything and so is citric acid as preservatives. If there are anyone of you out there that is or has experience similar to what I am, please let me know. My doctors cannot help me,nor do they seem to really even care. My wife has given them a lot of information she has been downloading from the computer. Hope this wears off soon. Every time I take one step forward, I wind up taking two steps back. Where is the help out there that we need? Since we are the minority who suffers from these drugs, doctors don't care until they have to deal with it. What is wrong with our medical society?

I was on topamax for about 2 years. I took it for frequent migraines caused by my sinus's. I had all the normal side affects but got used to it after awhile. The only one i didn't get used to was the hair loss. During this time I started allergy injections and now i'm up to my maintenance level. So i decided to ween myself slowly off the topamax. I have been off for about 2 months now and I have been fine on the headache side, but i have started to get other symptoms (i think withdrawal symptoms). They have progressively gotten higher in number as the days go by. First my hair loss has not stopped. I gained about 10-15lbs, I am edgy and climbing the walls all day. I have a really hard time relaxing. I recently developed horrible insomnia, and about a week ago i started having digestive problems including water retention, bloating, gas, irregular bowl movements, and acid reflux. And I've recently had bouts of tightness in my chest and throat which make it difficult to breath (lasts about an hour). I didn't have any of these symptoms while i was on the topamax (except the hair loss), nor did I have them before it.
I am seeing an endocrinologist in a few weeks to make sure nothing on that front is causing any of this, but i really feel it's from taking and going off the topamax. If you can find other ways to deal with your migraines, DO!

Hi I am a 44 year old asthma patient. I have had asthma since the age 2 and have been on & off prednisone since that time. As a child until age 20 I was on predinsone daily. My question is has anyone experienced nerve problems due to long time use? I do have muscle weakness and spasms, but I am interested in if anyone has had nerve problems. Please email me at ****** and refer to prednisone.

I had been on a prednisone dose pack (not too strong??) about a month ago for a neck injury to take away some inflammation. No side effects to mention and my neck felt tons better. Yesterday I went back to my dentist after 5 days of pain from a root canal. He put me on a prednisone dose pack saying there was some inflammation in the bone, very common, and the prednisone should take care of it. I took my dose yesterday, didn't sleep well (common side effect it seems) but then today my heart is racing and feels like it skips a beat. I have read this happening to folks on much higher doses, anyone have this kind of side effect with 20 mg/day?

LEVAQUIN SIDE EFFECTS - As I posted yesterday, after taking one Levaquin - 750 mg, I had hallucinations, sleeplessness, extremely severe headache, and now today I woke up with "thrush mouth/yeast infection" in my mouth - plus aching gums and teeth.

Please, FDA or drug company that makes this, read these boards. This is the TIP of the ICEBERG. Think of the thousands or millions who don't take time to report the side effects of this drug. It would not surprise me if suicides and death are not brought on from LEVAQUIN.

I am thankful I had the good sense to stop this drug after one dose or I might be dead. The hallucinations and headache were the most horrific of my life. I can't imagine what I would be like if I had taken all 7 pills.

Some common sense observations about Singulair side effects. (As everything on the internet, this is only my opinion.)

Conclusion up front: Ethics in science SUCKS these day. Put enough money on the table and what happens? I don’t mean all scientists, just the few. But, the Merck ghost writers are the tip of the iceberg for those in the schm#ck category. Maybe, if we reveal the extremes of abuse of laboratory animals, the ASPCA will organize and save us all. How about if they find out about the pharma labs that just beat the cr@p out of the lab animals to produce a stress response to find out what chemicals are produced? What was that all about?? Probably military—send our soldiers out to war over politics/oil, then we will have a pill to give them every night to put them back together again for the next day??

1.The cysLT1 receptor, which Singulair blocks, is a gene, found on the x chromosome (?), part of our inherited innate immune system. It is evolution. The hypersensitive individual overreacts to environmental stimuli causing unpleasant or dangerous symptoms. It is advantageous to intervene to prevent that. Merck’s idea was to block cysLT1 so that the chemicals secreted by the mast cell cannot reach the tissues in the lungs and nasal passages to cause the inflammatory responses-asthma being the more severe.

2.How did Merck develop such a drug? The cysLT1 receptor , a gene, has a profile, a chemical map of the components. Montelukast, was modeled to chemically bond with the receptor so that it does not function. That bond will endure until the liver enzymes break it down. Montelukast blocks the leukotriene response until it is time to take another pill. All that sounds good so far.

3.Now comes the first of the too good to be trues. Montelukast was formulated for a specific gene profile. However, cysLT1 has variations, numbers unknown, but more than several. Even Merck recognizes that it is not effective for everyone because the clinical data shows that. Mis-matches with the gene profile can cause montelukast to be recognized as an allergen. Then, the body mounts an immune response against montelukast.

4.Many of the symptoms that we see here are allergic reactions to montelukast, headache (18%), types of neuro-muscular (10%), hives, nausea, vomiting, leg pain, stomach cramps, and more. Some people will recognize montelukast instantly as an allergen. If the mis-match is slight, the allergic reaction could be acquired or build over time. Montelukast will ALWAYS be an allergen to those people. Doctors will do great harm if they treat allergic reaction to montelukast with other drugs. Those people must STOP taking montelukast.

5.The second too good to be true, is that cystLT1 receptor, involved in the leukotriene response, is only a very tiny part of the immune system, genetically programmed to function as a WHOLE. Now what? It is highly unlikely that montelukast can block the leukotriene receptor - cysLT1 in the brain, lungs, spleen, intestinal mucosa, etc. and not cause some kind of re-structuring of the immune system to compensate for that. Those who take Singulair can expect that they are a new adaptation of human being who can operate without the cysLT1 receptor. Or, they can expect long term damage. How scary is that?

6.What would happen if Merck revealed that montelukast, by definition , cannot work for everybody because it is based on a gene profile with variations? What would happen if patients and doctors started to think about the immune system as a whole? Then Singulair – which means “single thing you need for air – breathe” the logo is even Singul-AIR, would not be the huge money maker that it is. Doctors would find a way to use it, for whom it is effective, in an appropriate way to consider the long term effects. For some people, this drug could have a place. But this drug does not deserve to be a CASH COW-money, money, money!

7.What in the heck is wrong with the FDA? Are they under a spell or hiding under a rock?

I am glad to hear that CBS is looking into Lipitor. My feeling is that the posts that you read on this board are just the tip of the iceberg. For every one post here there are probably, at least, 10,000 others with similar symptoms. At some point there has to be a class action suit against these drug companies

I posted #5174 back in April. At that time my lower back was killing me. After stopping Lipitor the worst of the back pain went away. Unfortunately, there still is a constant low-level of pain. I am afraid that the Lipitor has done permanent damage. Also, the tininitus is still in my left ear.

Aside from the constant low back pain and the tininitus the muscle aches, toe cramps, and joint pain have gone away.