Tolerance symptoms and conditions

I started taking 400mg yesterday for a sinus infection. Fifteen minutes after my FIRST dose, my stomach started cramping. About five hours later I noticed muscle pain in my thighs all the way down into my toes. It was like I worked out at a gym. This morning I have a metallic taste in my mouth that even lemon water won't cure. I have a VERY HIGH tolerance for medication and usually have to double whatever is prescribed. Fortunately I did not do that with this med since it was new to me. I will not be taking anymore. I will go back to the amox and deal with the infection. I read that apple cider vinegar was good for that - without the side effects. Seriously, beware if you are sensitive to drugs. This one surprised me.

I took Lisinopril for approximately 7 months. My main symptoms were that I could not think clearly (it has been very difficult to perform my job) and I was tired all of the time. When I finally decided to stop taking it, the fog lifted from my eyes and I had more energy. I like to have a drink once in a while and I had noticed that one of the side effects of Lisinopril was that I no longer had any tolerance for alcohol (I know I'm not supposed to drink). Drinking one beer gave me the same sensation as if I had four beers. One Friday (I was going on vacation) I decided to skip my dose so that I could go out and drink and have fun like I'm used to doing. The next morning the clarity of my thinking and my level of energy was dramatically increased. This is how I found out by accident (you could say irresponsibility) that Lisinopril was dragging me down. I have not touched Lisinopril since and I am working with my doctor on finding an alternative.

I had Mirena inserted July 2009 and I have been spotting off and on ever since, which my doctor told me would happen for about 6 months or so. The insertion itself was painless, I barely noticed that my doctor did it. I don't know if I just have a high tolerance for pain or if I just have a great doctor, because my experience sounds nothing like some of the other women.

As far as other symptoms, I think so far everything is going good and I am very pleased with it. My periods are lighter, but the spotting off and on is getting a little annoying. I think so many people are quick to blame something on their health problems,and not look at the big picture.

Mirena== good choice for me!

I've finally had the mirena removed - about 2 months ago. I'd had a very light period around the time that it was removed, but none since. My body aches a little, still, but it's more tolerable that it had been before. Initially i could NOT stop urinating! i lost easily 3 lbs of nothing but water weight in the first couple of weeks. As excited as i was about that, it's a bit at a standstill now, losing the weight, but overall, my tolerance has grown, my sex drive has returned and mood swings have drastically been more controllable. I enjoy playing with my daughters again, and i've been able to get a lot more around the house cleaned. I feel about 70% better now and i'll take that any day over what i had been feeling. I do still get melancholy every now and then but not as severely.
in the past 2 week i've started taking vitamins - w/ a little extra b12 and calcium w/ D - to try and help my body balance out. that definitely makes a difference in how i feel through the day.
1 thing i can't get over is the constant thirsty feeling and almost a copper taste that lingers in my mouth, but i can only assume that after retaining water my body is re-adjusting to the intake/release ratio. good thing i like water and tea :) over all - i love having the mirena! ----- REMOVED!

I was prescribed Bactrim DS to treat an ORSA Staph infection following some vein surgery in my right leg. The original prescription was 1 pill 2xday with a refill after 7 days if needed. Since the infection did not seem to be responding very well and I had not developed any side effects (at day 7) I told my Dr. I was going to refill it. I continued to take it another 4-5 days when I then developed bumps and a slight rash on both of my lower legs. I went to the Dr. (my primary physician - not the vascular surgeon - who had originally prescribed the Bactrim) and was told it didn't "appear" to be an allergic reaction to the medication since it wasn't on my torso. Within two days the rash had intensified and spread all over my legs. Then within another 3 days it spread to my arms. The itching is relentless and varies between raw, searing, burning pain and plain old itch. Last night I cried myself to sleep for lack of any way to relieve it. The newest side effects are nagging pain in my right knee ( I've never had any joint pains before) and a feeling of tightness in my chest. I'll be calling my Dr. back tomorrow, if only to find out just how long I can expect this joy to last.

I will never, ever, take Bactrim or any related medications again.

Someday, some genius research scientist will invent a test to determine an individual's tolerance to this drug - BEFORE they take it and develop side effects.

I was injected with Lupron and the shot last for three months. I had the shot in order to stop my periods to increase my blood count for surgery to remove fibroids. The first two weeks, I spent having a very light cycle. I'm 2 1/2 months in and haven't had one since. I have, however, had menstrual cycles and never had them when I had my cycles before Lupron. I have a high tolerance for pain, but I was constantly popping Motrin to deal with the cramps. I experience pressure in my head during the second month, but it has gone away. My sex drive sky rocketed since I've been on the shot, but I have some vaginal dryness. My energy has also decreased since being on the shot and I don't work out like I use to. The three months is almost up so hopefully I can get back to normal once it's over.

Hello all, I Don't no where to really begin. I just started taking ambien cr for the first time last Wednesday. I was given the 12.5 mgs. I used to be on Restoril 30mg, but ive mustve built a high tolerance quickly because it stopped working. So i went on Ambien Cr. THe night before i took a restoril before my doctors appointment, then on the next day when i was prescribed ambien cr i took it that night, just one pill. It took a while for it to kick in, id say like a couple of hours, but i did manage to fall asleep. Next night I took one again, this time it was taking it a bit longer for it to work, so i chanced it and took a second pill. 30 mins later I finally started feeling the effects of the medicine kickin in which were drowsiness, blurred and double vision, and dizziness. So i thought to myself Maybe i need to take 2 of the 12.5mg every night. SO the next night i tried to experiment, i took 2 pills at one time, and in 30-40 mins time.. i felt the effects kicking in and went to sleep and woke up good., the next night did that again and fell asleep like a baby. but the next night. those two pills two much longer to kick in, id say it took about 5 hours. Im thinking and thinking why would this suddenly happen. I cant grow a high tolerance that quickly! Then it hit me that i was on Restoril for about 3 1/2 months and maybe my body is going through some withdrawal effects. Today I did feel really anxious. I took 2 ambien at 10:30pm Saturday night and im still up and its 5:20am Sunday. LOL. What do you guys think is happening to me? Could it be just that my body is detoxing itself of the restoril and im feeling some withdrawal effects?

Hi all,
3 months ago I had my second Mirena fitted. Since then I've found that I have been low. moody and have little tolerance. Even my friends have noticed the change in me and are concerned. I could understand this if there were reasons for this but there aren't. I therefore thought i would have a look on this site and see if anyone else suffered the same, and consider taking the coil out.

Over the past few years I occasionally suffer from sore throats with a metallic taste and aching at the same time? Had every test done even allergy tests and nothing! Could this be the coil as tests show its nothing else?

Would be interested to know if anyone else has had any similar symptoms?
Many thanks
J.

I had my Mirena put in on April 7th 2009, so about 3.5 weeks ago. Immediately I regretted my decision, the intense pain and cramping at insertion was not what I was expecting or bargained for. I had to sit in the doctors office for 45 minutes till I could gain my composure back and I have a high tolerance of pain. That night I could not sleep, I got 3 hrs sleep for the first two nights, only 6 on night 3 and it hasn't gotten any better since. Hot flashes, headaches, back pain, moodiness with my children and the constant bleeding since insertion combined with the insomnia is enough to make me have this thing removed. I called my doctor after another night of 3 hrs sleep last night and I am getting it removed at 1:30 today! I can not wait, especially after reading all of the stories on here I know this is the right decision for me. My greatest concern is now what? Will my insurance pay for me to have tubal ligation now after having paid for this only 3 weeks ago? That is the chance I will have to take. A mother of 3 little ones needs her sleep for her sanity!

I have to say that getting the mirena inserted was the biggest mistake I have ever made. I have gained 30 pounds, my hands and ankles swell all the time, I feel bloated all the time, I'm not as focused, and now my doc has called me today to tell me that I have low thyroid levels. When the Mirena was inserted the pain was almost inbearble, I broke out in a cold sweat and almost passed out (and I have a high tolerance for pain). I have called my GYN today to have my mirena removed so I can get back to my normal self. Thank you ladies for posting your side effects for at first I thought it was just my body changing since I am 37 yrs old.

tolerance

I'm so glad to have read this. I have been feeling horrible, my legs ache non stop, my eyes hurt, my head hurts, my back, my period is heavier, and a huge increase in clots too. It feels like i constantly need to stretch which i do and does not help! The pain is excruciating.
I have recently just started taking Yaz again. I have taken it in the past and never felt this way. All of a sudden I take it again, and i feel like I'm in a daze mentally and my body aches. I don't know if it's due to the birth control, but it is following the same symptoms as others are experiencing who are taking it.
Now I believe I have a high tolerance for pain, but last night was day 4 of the intense pain and cried myself to sleep because of the aches. It's very annoying and sometimes brings nausea. It makes it hard to focus being a full time college student as well as working full time. I do not think I'll continue with Yaz if this is the case.

Man, I feel like a woman!! I got that terrible IUD out today! Not joking when I say as it left my body, it was almost like my old self re-entered!! I can't wait to see how much my body changes inside & out! If your having depression, low tolerance, no sex drive, seeing things, and all the other effects it puts you through, GET IT OUT!!
It is seriously hardly painful, as soon as you take a deep breath in, it's out just like that, go ahead take a quick deep breath in-that's how fast it is. No tears, not even eye watering!! Good luck to all of that still have it, but please get it out before it ruins you and everyone else around you!!

~God Bless

Very high tolerance for medications incl 60mg morphine, 20mg oxycontin 4x day, however, I just cannot seem to tolerate Fentanyl. Have tried it two times in past, both the 25mcg and 50mcg. The first week or so is great, after that the side effects are more than I can tolerate. All of these side effects were extreme and unbearable not just mild. They affected my ability to function and sent me to bed on more than one occasion. Extreme fatigue, nausea, sweating, anxiety and weakness. I felt as though I had a very bad case of the stomach flu. Both occasions I stuck it out for 2-4 weeks till I finally had to quit using it. Any suggestions as to why would appreciated. Some of my side effects aren't even listed in brochure.

I got my IUD on Nov 20th and it did hurt me when they inserted the Mirena. I don’t know if I have a high tolerance for pain or if it was just my wonderful doctor (Shout out to Washington Hospital Center). Anyway, my doctor told me to come back to see in a month if I wanted to keep the Mirena. Well, I can honestly say that I am considering taking my IUD out on Dec 20th. I had 1 episode of fatigue while I was at work and I literally thought I was about to die. It scared me so bad. I didn’t know rather to call the ambulance or just take it easy for a while and drive home. The second incident was being very snappy and I can’t afford to be that way raising 3 little kids. I have never been a person to go off at the drop of a hat. I’m always very calm. Also, I have been bleeding for the past 6 days and it is very heavy. I am 31 years old and have always bled for 4 days and to tell you the truth I thought that was too long. I just can’t imagine having to deal with staying on my menstrual for 6 or more days. Far as my sex drive, I have notice that it increase. That’s the only plus that I am having with this thing. My advice to anyone that is considering getting the Mirena is to really consider all these side effects and if you experience 1 take it out in a month. I’m going to write to the company that made Mirena and to ask them to research this device some more. This is RIDICULOUS.

when I was in my early 20's i got a sever case of bad acne! I was prescribed 100mg of Doxy 2 times a day. Of course I learned very quickly to eat before having it. Other than that no side effects. I had flawless skin for about 2 years, at which point i had built up a tolerance to it. When I noticed a few pimples I went straight to my derm before it got out of hand. My derm switched me to minocycline and after about another year of perfect skin I got off of meds all together. I have great skin now, just use proactive and nothing else.

Well now my 14yr old has started breaking out..nothing topical worked, I want to protect her from all of the emotional damage that acne caused for me. Put her on doxy 100mg 2x a day. Shes been on it for about 2 weeks and it seems like the big ones went away but there is an over abundance of small ones now and they are flaring up. Is that normal..I don't remember this happening to me but it was so long ago. Does it get worse before it gets better? Anyone experience this?

I am so glad I came across with website. I thought I was going crazy. I started Loestrin 24 11 days ago with no side effects until 3 days ago. I then started experiencing anxiety attacks which I have never had before. Also the past 3 days I have been crying and totally stressed out for no apparent reason. I am so tired and just want to sleep all the time. I have had no tolerance with my children and I too wish I could just climb to the top of a mountain and stay there. I took my last pill yesterday and have just disposed of the rest. I am praying these symptoms resolve soon and I can go back to feeling normal. I am too scared to even try another bcp.

My husband has been taking Lamictal now for 2 years. He had two seizures within 6 mo in his late 30's, one of which resulted in a car crash. Of course he is grateful for such medicine but as a partner and wife, I noticed lots of changes in him after he began the medication. He was irritable, had very low tolerance and a short fuse, was extremely distant and often mean - which in the end caused us to separate for some months. Although we are back together now and our relationship is doing very well, I notice other side effects, for example, he sleeps every time he sits still, etc.

HOWEVER, the real reason I am consulting this forum is to ask anyone (especially men) if they experience side effects related to sex. I know this is a tabu topic but things just aren't working as they used to and I am looking for solutions as he doesn't seem to question the side effects of this drug. This is starting to become an issue psychological issue now as well. Has anyone else experienced lower sex drives and complications during sex?

For about eight months or so I have been experiencing pretty intense anxiety. Thus, I was prescribed the generic Clonopin (Clonozepam). After building a tolerance to the increasing dosages I was prescribed, I found myself needing to take up to 10 mg daily. I became as many people told me, "a zombie". I developed extreme depression and constant bad thoughts. After talking to my doctor i was prescribed Paxil. I did not like this whatsoever so about two months ago I stopped taking the Clonopin abruptly. I experienced pretty severe withdrawals, or what i thought to be withdrawals (shaking, sweating, very irritable, constant pain, and anxiety). It was absolute torture. After talking to my doctor i was then prescribed Xanax, which i am currently on. My depression seems to have stayed constant. It was suggested to me to take Wellbutrin rather than Paxil, which of course i would have to wean off from my 100mg a day. Two weeks ago, or so, i started taking the Wellbutrin at 150mg once a day in the morning. After the first week or so i felt "up" more or less, in comparison to how i had been feeling. I began to research about possible side effects. I didn't really find many except mildy vivid dreams and anxiety, which threw me for a loop since i was trying to fight that, right? Well, after the first week i had been lowered on the Paxil to 50mg daily and raised to 300mg of Wellbutrin, once a day in the morning around 7am. I am now on my second week of the anti-depressant, but ironically i feel as if i am more depressed, just in other ways. I feel very lethargic, and i feel as if i am to be very "spacey". I'm not quite sure if it is the mixture of the medications or one in particular. But the most noticeable side effects of the Wellbutrin have been IRRITABILITY!!, veryyyyy indecisive, and ridiculously vivid dreams with little to no meaning. They seem to last for weeks on end at times, and i often find it hard to differentiate what is a dream and what is reality. By no means am i trying to say that this medication will not work for you. Anything to make someone feel better. Whatever works for you is great and you should persue it! Any suggestions or comments to this would be great. And is anyone feeling the same side effects??

Cameron

After reading a lot of these comments I can say that I'M NOT CRAZY! Yasmin really was the cause of a lot of problems that I had. I switched from Ortho Tri Cyclin to Yasmin about two years ago because I wanted lighter periods. It took me almost that entire time to figure out why I was feeling so much different. I never had problems with spot bleeding on Ortho and Yasmin didn't change that. I did start having really bad headaches a few days before I would start my period. It also cause my hair to stop growing and become very thin. It took me forever to realize that my hair started to change about the time I changed my birth control. I have tried everything to get my hair to grow again! Nothing seems to help. I had acne in high school (around age 18) but after and up until about two years ago (age 21) my face has always been clear. After switching to Yasmin, now about two weeks before my period I break out, mostly around my jaw line ITS LIKE HIGH SCHOOL ALL OVER AGAIN. I also found that it has an effect on the face cleaner that I use. I have used proactive for the past 4-5 years out of habit and found that two weeks before my period my face has a horrible reaction to the cleanser. Its gets really red and irritated and it itches like crazy. That only lasts for a day or two tops but I never had that problem before. The worst part about Yasmin in my opinion, besides the hair loss, is that it turned me into a down right mean person. I treat my boyfriend like absolute crap, and for no good reason. I have no tolerance for anything, I snap at him constantly and I yell at him for everything. I met him about three years ago and he always asks me why I changed so much from when we met. I guess I figured it out! I'm getting off this stuff and thinking about switching to ortho tri cyclin LO, is that any better?

Confusion, trouble thinking, trouble concentrating, decreased cognitive function, mental sluggishness, foggy perception of reality, trouble solving problems or situations which require logical thinking and sequencing, memory loss, depression, irritability, low tolerance, lack of patience. jeez.....the list goes on. All that since I started Lisinopril. Never had it before. All of my symptoms seemed to be more neurological than physical, like other people's. Of course, everyone's body is different. I got off this stuff awhile back, but I still have the symptoms. I hope these symptoms are reversible. This is terrible. I need to get back to my normal life once again. It's like this junk is Alzheimer's/Dementia by design. Really.

I've had migraines almost all my life. I've tried numerous meds but have found that Fiorcet helps the most. The only problem with it is that it is somewhat addictive and I've built a tolerance to it. So, recently my dr. prescribed Midrin. I've been taking one a day for the last 3 days and am experiencing terrible side effects - nausea, confusion, extreme fatigue, tiredness, laziness, lack of motivation and, worst of all, my headaches have gotten worse!!! I'm waiting on a call-back from my dr. on what to do but I can't imagine this medicine possibly working for me.

I have now finished my fourth month on Loestrin 24Fe. Still no period. Prior to being on it, I was on Seasonale--now, sure it's great not getting your period for 3 months, but that is another side effect page! Since switching to LoE24, for the first 2 months I had CRAZY mood swings and 6 out of the 8 signs of peri-menopause (I'm only 37). I did find out that Seasonale has a higher dosage of hormones and LoE 24 has less.

When I first switched, I LOVED the Loestrin--it made me feel so much more alive and like me again from the Seasonale. After two weeks, I started the "yogurt-like" discharge that went on for two months--no, not a yeast infection or anything, just weird hormonal stuff according to my doctor. After the two months, the discharge and the major mood swings went away all of a sudden, I was just fine one day and those symptoms have gone. Still, no period...it's been four months and 6 pregnancy tests. Now, I'm still a little moody but I'm not sure if it is pill related or frustration at not knowing what is wrong.

A girlfriend of mine loved this pill, so I guess everyone is different.

I have been taking percocet for pain and it is prescribed for me to take 1 or 2 every 6 hours not to exceed 8 per day. However, since the effects of 1 or 2 do not last 6 hours I take 1 every 3 hours at the most. Sometimes I skip a dose if I am managing pain without them. At first, they seemed powerful and made my head feel foggy. I only took them at night to help sleep with pain. Since taking them again, I have developed a tolerance very quickly. I need to take more to sustain pain relief, but I do not have too many unpleasant side effects. They help me sleep and manage pain, but I get extremely constipated, have strange dreams and get impatient and emotional pretty easy -- but the emotional impatience is also a side effect of extreme pain.

i was prescribed effexor xr by the mayo clinic in mn. while living there for a year. i had been on three other antidepressants before and this one has really given me a sense of peace. i have had to go off of a lot of medicines and quite smoking cold turkey so maybe i have a stronger tolerance. i haven't had one bad side effect. in fact, i have probably been healthier since it kicked in two years ago due to my mood and mind being in a better state. don't get me wrong, i still have low times but not any lower than the person who doesn't suffer depression. it also helps with anxiety but i do take another med for that called klonopin 2mg. i think it takes awhile for the person to find whats right for them. i suffered horribly through wellbutrin, thought my head was going to blow off when i didn't feel bugs crawling around. prozac put weight on me but helped, just made me a little to jittery and the other one i took was zoloft. i didn't have any side effects with that just didn't seem to keep me above a sadness level i needed so that is when they switched me to effexor. please just know there is help for all and bravo to those who can go without but i don't want to be sad and unhappy ever again to the degree of not wanting to get out of bed.