Tremor symptoms and conditions

SINGULAIR'S LABEL HAS BEEN UPDATED:

The following has been added to the "Precautions" section of Singulair's label:

"Neuropsychiatric Events
Neuropsychiatric events have been reported in adult, adolescent, and pediatric patients taking SINGULAIR. Post-marketing reports with SINGULAIR use include agitation, aggressive behavior or hostility, anxiousness, depression, dream abnormalities, hallucinations, insomnia, irritability, restlessness, somnambulism, suicidal thinking and behavior (including suicide), and tremor. The clinical details of some post-marketing reports involving SINGULAIR appear consistent with a drug-induced effect.

Patients and prescribes should be alert for neuropsychiatric events. Patients should be instructed to notify their prescribe if these changes occur. Prescribes should carefully evaluate the risks and benefits of continuing treatment with SINGULAIR if such events occur (see ADVERSE REACTIONS, Post- Marketing Experience)."

This is to serve as a personal warning to ANYONE taking
Effexor XR or thinking about taking it.

After my husband and I experienced HORRIBLE withdrawal symptoms within a week from coming off of our medication, and has continued for 4 months now. I feet compelled to inform people about the risks that this drug carries with it.

This drug helped my husband and I immensely while we were on it, but I just wish that I had been more knowledgeable about the risks of going off this medication so abruptly.

I understand that the medical professional that is prescribing you the drug is supposed to inform you that you are not to stop taking the medication abruptly (which is exactly what I was told). IN NO WAY was I told the consequences of NOT taking the medication.

So here are some of the symptoms that I experienced within the first two days (there are many more symptoms that other Effexor XR patients have experienced, but I feel that it is only right to list mine):

• Akathisia - a syndrome characterized by unpleasant sensations of "inner" restlessness that manifests itself with an inability to sit still or remain motionless.
• Ataxia – Loss of the ability to move the body with coordination.
• "Brain Zaps", "Brain Shocks," "Brain Shivers" or "Head Shocks" Descriptions include dizziness, electric shock-like sensations, sweating, nausea, insomnia, tremor, confusion, and vertigo.
• Cold Sweat – The skin is clammy and moist and you feel chilled. This is a reaction to a shock or pain as well as to fear and nervousness.
• Colitis – A condition where the large intestine becomes irritated from the use of the drug.
• Dehydration – An extreme loss of water from the body or the organs of the body as in sickness or not drinking enough fluids.
• Depersonalization - A feeling of watching oneself act, while having no control over a situation. (A sufferer feels that he or she has changed and the world has become less real, vague, dreamlike, or lacking in significance.)
• Diplopia – A condition where a person is looking a one object and instead of normally seeing just the one object he sees two. This is also call double vision.
• Disequilibrium - Dizziness, light-headedness and vertigo with a sense of losing balance.
• Dysarthria – The inability to control the mouth muscles when forming words so the words are not clearly spoken and heard.
• Gastric Irritation – An inflamed and sore stomach.
• Hyperhidrosis – The triggering of an excess of sweat being produced on the soles of the feet and/or the palms.
• Hypoesthesia – A partial loss of sensation or general loss of awareness.
• Influenza-like - Fatigue, lethargy, chills, sweating, headache, weakness and palpitations.
• Insomnia – Not able to fall asleep or sleeping for a shorter time than desired, thus not being able to properly rest and feeling un-refreshed. As a result, a person can become irritable, have difficulty concentrating and feel a lack of energy.
• Irritable Bowel Syndrome – A painful condition where the either the muscles or the nerves of the lower intestines, are not responding normally. This results in an alternating condition of diarrhea followed by constipation, back and forth.
• Mania – Unusually irrational, excessive and/or exaggerated behavior or moods ranging from enthusiasm, sexuality, gaiety, impulsiveness and irritability to violence.
• Mood Swings – An emotional shifting as from a state of happiness to a state of depression for a period of time.
• Night Sweats – With night sweats you become wide awake in the middle of the night shivering and cold and wet with your sheets/pajamas soaked in perspiration making it difficult to go back to sleep.
• Nightmare – Dreams that make you afraid or leave feelings of fear, terror, and upset long after waking up.
• Abnormal Orgasm – Unable to have an orgasm with normal sexual stimulation.
• Pain in Extremity – A painful feeling in the legs, arms, hands, and/or feet.
• Paresthesia - A sensation of tingling, pricking, or numbness of a person’s skin with no apparent long-term physical effect.
• Photopsia – A condition where a person sees lights, sparks, or colors in front of their eyes.
• Pressure of Speech – A condition where the individual cannot voice his ideas fast enough with the pressure of there being not enough time to say it.
• Pyrexia – Fever or the increase in body temperature that is usually a sign of infection.

Now some of you may be thinking that I might be overreacting, but I assure you that I am not. Quite the opposite actually, I feel that there are probably more symptoms that I am leaving out.
When I went online to research the symptoms that we had been experiencing, there was little information that I could find. I went onto the website for Wyeth (the company that produces Effexor XR) and the only thing that I could find was, and I quote,

“When people suddenly stop using or quickly lower their daily dose of EFFEXOR XR, discontinuation symptoms may occur. Talk to your doctor before discontinuing or reducing your dose of EFFEXOR XR.”

Wyeth also states that Effexor XR is, and I quote AGAIN,

“ Effexor XR Is Not Addictive. Effexor XR and other antidepressants are not addictive. You cannot become addicted to an antidepressant even if you take it for long-term maintenance therapy. An antidepressant is not a controlled substance like a narcotic or a stimulant.”

I am very sorry Wyeth, but I disagree.

Ive been on Topamax since for 3 months for migraines and have lost 30 pounds, I simply am not hungry. At this point its not worrisome as I did have a little extra weight to lose, but I cant keep it up forever. My doctor lowered my dose from 100 Mg, to 75 mg, which I split and take 50 mg in the morning and 25 in the evening, it has not made a difference. I had a tremor prior to Topamax, which my neurologist thought would be less with the Topamax but in fact it was increased, so I had to start another drug, Mysoline to counteract the tremor. Ive been on that for about a month and it seems to be helping some, Im at least back to baseline. I recently learned that my potassium level has decreased which is causing muscle cramps and can cause many other more life threatening problems, so please watch out for that! It is a listed, albeit less common side effect of Topamax. (0.4%). You Dr. should have checked basic metabolic panel (BMP) and should check it regularly. Oh, and IM MIGRAINE FREE!

I have been on Lamictal 200mg per day for about 3 years along with Wellbutrin and Lexapro. Over the past few months, I have noticed numerous things happening to my mind and body and finally put the pieces of the puzzle together...side effects of Lamictal. Short term memory is gone which is the scariest. Difficulty putting coherent sentences together. Fumbling for words. Spelling is awful. Heaviness in legs. Trouble writing. Inability to communicate well with the spoken word. Slow thought process. Shakiness - Hands shaking - Tremor. Speech disturbance. Weight gain. Coordination problems. Dry mouth is worse. Back pain. Increase in sweating including night sweats. Irritability. Impaired concentration. Forgetfulness.

This is so embarrassing when I'm in meetings. I start to sweat and can't seem to get my words out. I am also in a master's program and it is getting really hard to concentrate enough to write the papers. I am starting a doctorate program in Aug. which will not happen if these side effects don't go away. I called my doctor on Friday and we cut the dose in half and evaluate in 2 weeks. I want off of this drug! I need all of the symptoms described above to go away, especially my short term memory loss. I am very scared at this point.

My doctor had me on a 10-day course of amoxicillin for a sinus infection. By the last day, I had contracted pneumonia and the sinus infection had rebounded until it was worse than ever. So, like many others who have posted here, my doctor prescribed Avelox. Fortunately I read the entire printout from the pharmacy, including all warnings of potential side-effects, both minor and serious. I grew concerned on day three when I had numbness and tingling all down my right arm, and following the warnings, called my doctor. Fortunately, my doc is a smart guy: he told me to stop the course of Avelox immediately, and if the nerve symptoms returned, I should go to the ER.

Some of the symptoms others here have mentioned -- many far, far more serious than mine -- seem neurological, as if the drug is also messing with brain function rather than just causing an allergic reaction (especially the seriously altered mental states).

A symptom that has occurred occasionally during the past weeks since I stopped the Avelox is an odd tremor in my eyes when I'm tired. My eyeballs shake quickly and sharply from side to side for about 10 seconds at a time. I had a similar reaction many years ago, when my doctor at the time prescribed a high dose of Paxil (anti-anxiety). The difference was that then the eye tremors stopped two days after I stopped the drug; the symptoms now started long after the Avelox was out of my system.

I linked to this webpage specifically because I was wondering how common adverse reactions to Avelox are. God knows we need some new antibiotics to fight the increasingly more resistant strains of bacteria. But if our bad experiences are as common as I fear, even though some people experience wonderful results, this is one drug that should be prescribed with extreme care. Not only that, but both the physician and the pharmacist should be especially diligent in explaining the more dangerous adverse effects so that patients (who don't always have a half hour to read through hundreds of single-spaced lines of instructions on drug sheets) are well-informed enough to participate in our own care. If that just means telling our doctors that the risks outweigh the benefits, please prescribe something else, so be it.

I've been on Zoloft for about a month now for OCD and anxiety. I previously used Luvox, but had to quit due to severe suicidal thoughts and hurting myself.
I've noticed recently that my sex drive is INSANE! However, it takes me a very long time to acheive an orgasm.
The only side effect I can certainly link to Zoloft and not one of my other meds is that my muscles randomly jump or minorly tremor.
Memory, 19

My 19 year old daughter received the first shot in March 2008. She immediately had a severe back pain. She had her first seizure in April. She got the second shot in May and had more seizures, fatigue, headaches, severe stabbing stomach pains, body aches and pains, tremor, hair loss, vision problems, 2 UTI's, mono like symptoms - swollen glands, bruising and bleeding gums are the most recent symptom. She had daily seizures throughout the summer and they are now about every 5-6 weeks. She is fighting to recover from this horrible nightmare called Gardasil. Thank goodness we figured this out and she did not get the third shot. If you want to sign the petition to get this vaccine in front of Congress go to: http://www.thepetitionsite.com/14/investigate-gardasil-vaccine-risks-now

I'm a 47 male and took Crestor for a year. I experienced muscle tremors, constant fatigue and muscle soreness. Not just a little sore but as if someone had hit me so hard as to leave a muscle bruise in both arms. One night my left arm and leg began to tremor and it was as if they were too heavy to move.

What I noticed was that all of my little aches and pains became severe aches.

I experienced blistering on my hands, a common side-effect of your liver rejecting the medication but my doctor didn't pickup on the symptom. Instead, he gave me a steroid-based topical cream that actually eliminated the blisters but they would return within weeks.

I experienced lapses in my memory and I started to forget words. I would forget the names of things and I found myself substituting the word 'thingy' when I could remember what something was called (like a phone).

I visited the hospital 4 times and my doctor countless time. Each time my doctor treated the current symptom and not the person as a whole.

It became too much to bare when I started having chest pains that felt like something was crushing my chest. At this point I started to do some research and found forums like this one.

During my time of the worse pain, I felt like I was actually dying. I started to get my effects in order and finalized my estate.

I stopped my Crestor about a year ago, after about 3-6 months my muscles began to feel better. After a year, I am finally starting to feel like my old self again (not that I was all that well before).

Statin affect people differently, but there is NO DOUBT that these drugs can have adverse effects on people. Listen to the commercial for Lipitor, "contact your doctor if you have muscle fatigue or weakness"......

I was prescribed Avelox for a Sinus/ear infection. I was given 1 pill a day for 5 days. I took the first pill and within 30 minutes I was starting to feel very "out of it". I started to get very anxious and began pacing in my house. I couldn't sit still without becoming agitated and disorientated but I was feeling so spacey that I didn't really know what I was doing.

My arms and legs started to itch, then tense up and began to tremor. I even started arguing with myself OUT LOUD about whether or no I should go to the ER. Finally I just made myself lay down in bed and slept for about 14 hours.

The next morning I work up and felt like I had been in a fight. My muscles were sore and weak and I had flu like symptoms that kept me bed bound for 3 full days after taking only 1 pill.

My hubby took Cipralex (Lexapro) for three weeks and one morning he woke up with a serve tremor in his left arm. He stopped taking it but now he is showing more and more signs of Parkinson's. And way faster then normal onset. in less than a month and a half he has lost arm swing on the right side, has internal tremors, no stop tremors on the left arm, left toes curling under....... He is only 33.
Has anyone else had anything like this???

twitching muscle loss abnormal emg weakness tongue tongling tremor toe tingling lump in throat

I am a 54 year old male who started taking Lipitor about 4 years ago. It seemed OK at first, but over the next several years I began to have increasing amounts of joint pain after exercise. Nor muscle pain, joint pain. And it seemed to be a result of exercise. By the time I stopped it, I was hurting after everything, not just exercise. I felt better within the first two weeks, but it took about 4 months for me to be able to exercise vigorously again. Over the years I seemed to have forgotten how much vitality I used to have. I am a physician, and because of the long lag time until I felt better, I wondered whether improvement might have related to other factors, so after about 5 months I decided to restart Lipitor. It surprised me that after just one dose, I got back all of the joint pain and fatigue when I was at my worst on Lipitor. I was really hurting. Needless to say, I didn't take any more.

Coincidentally, a physician friend of mine who had statin induced polyneuropathy had a similar experience. After his symptoms went away he found that after only one dose the entire polyneuropathy came back.

Stopping and restarting the drug is a way to test the correlation between the drug and the side effect. For such a large spectrum of side effects to recur after only a single dose, it argues that the problems that my friend and I had was due to some sort of immune memory response. I have not seen this in the medical literature.

I am off it now for about 8 months and am able to comfortably play singles tennis and jog - much more energy (and I took 200 mg of CoQ10 a day with the Lipitor).

I have just finished taking Levaquin for a 10day treatment for pneumonia. In the last 5 days or so I have noticed stiffness in my achilles tendon (no pain) until I get moving. I have also notice a tremor in my hands and no muscle weakness and shaking in my triceps and quads. Of course I hadn't read the precautions to this drug before noticing these symptoms. I contacted both my pharmacist and physician and neither seemed concerned and told me if I was really worried to go to the emergency room. I am wondering if these symptoms will disappear since I am no longer on the drug, how long it will take, and how long I should worry about tendon damage----is the possibility of rupture forever???

I've been on Zocor 40 mg. for 9 months. After being on it 4 months I began to have symptoms. Dizziness, vertigo, tingling in hands and on scalp, stabbing pains in head and chest, eyelid and finger twitching, throbbing of arteries above each ear and head tremors. Went to ER when vertigo and tremor got unbearable, they found nothing. Been to several doctors and not one of mentioned that these symptoms could be from Zocor.
Internet research enlightened me and I stopped taking it yesterday. Will advise if symptoms decrease.

I started taking the generic of Toprol (metaprolol) 3 months ago. I'm on 150mg per day for a rapid heartbeat, I'm 39 years old. It has helped my heart problems but I don't know if the side effects are worth it. I experience major fatigue that may last a week at a time and subside for a few days, aches in my back and neck (which I've learned may also be attributed to the Lipitor that I am also on), and my worse symptom is constant diarrhea. Some days I will run to the BR 15 times in one day. It seems to subside by dinner time, but that is probably because I stay away from food all afternoon. I'm fortunate that I am a stay at home mom I can't imagine having to go to work in this condition!

Here's a way out theory about my unique and to me mystifying medical situation....

I recently read where Singulair, an asthma medicine, is suspected of causing suicides, obviously an effect on the brain function. The FDA notes that over the past year, Merck has updated Singulair's prescribing information and patient information to include the following post marketing adverse events: TREMOR (March 2007), (April 2007), suicidally (October 2007), and anxiousness (February 2008). (the tremor highlight is mine since this is a major symptom of Parkinson's )

Well, I took Singulair from 1998 to 2004 and I wonder if maybe, just maybe Singulair could be a contributing factor to my strange Parkinson's but not Parkinson's problems that is
gait,
balance,
freezing of gait problems

Any thoughts or ideas on how I might follow up on my hypothesis?

lamictal controls seizures if you take it at the right time. i am on 200 at night and 200 in the morning plus epilim. sometimes i just sit and cry wen im trying to concentrate on reading books i have to study or trying to remember work i learnt at school which has left my brain. im failing school not matter how hard i try, i study all the time then the next day i have forgotten it. im so young and i havnt even started my future yet and i may have screwed it already. failing exams because i forgot wat i learnt the night before hurts so bad. its hard to say "hey everyone the reason i failed is because lamictal screws my memory" i know thats what it is. i was extremely intelligent before i started taking it, but now im a failure. i guess deep inside i know really im not a failure, but lamictal makes me one. : ( p.s add a constant hand tremor and sudden jerking movements every now and then.

I took Lipitor for about 2 years- 5 mg.
Leg cramps-soreness throughout my muscles- very sore buttocks-
my legs are shaky- if I use them too much; (as in walking 3 miles)
I am (was ) an avid body builder that could squat with 100 lbs- and now ( I am a health conscious -non drinking- NO other medication 104 lb slim female) have quivering legs if I stand for too long. I even had a muscle biopsy- and it cam back negative- I have not had a statin for 6 months- but I still have cramps- and abnormal liver values- and I have NO other conditions-I have been scanned from head to toe - open MRI- closed MRI -but the muscle stiffness- soreness- especially legs- continues-
does anyone know how long it lasts? I have also been tested for liver cancer- thank God-negative.
I really feel that Lipitor did this- has anyone else gone from fit as a fiddle to a quivering -achy person- I have gone through 5 doctors- internal - gastrointestinal - neurologist- hematologist and all is negative- just high liver values and muscle pain. Thank you so much.Maxine

My 44 year old, otherwise very healthy husband has been taking Lipitor (10mg) for several years. Currently been showing ALS-like symptoms. Left foot dragging, muscle cramps, twitches, etc. We are headed to Duke University to find out of he has ALS. He is off of Lipitor for 3 weeks now, taking CoQ10 and lots of vitamin C. If anyone else has had these symptoms and they've been rectified, could you share how long it took and how soon you began to feel the initial improvement? Thanks KCC>

Hi ..this is a follow up on my first posting of Jan 31 (see kookoo). I have been off Lipitor (20mg/day) for about 6 weeks now and I feel better than before but nowhere near normal yet. Hands are stronger but weakness in arms still persists. I have not had a bad tremor incident in about 2 or more weeks. But I have a lot of involuntary twitching and light burning in my arm muscles. I constantly feel like I have a stiff sore neck and the fatigue is unbearable some days. My neurologist (my hero since he is the only one who believes this is statin related) has sent me for additional tests like EMG, MRI and thoracic vascular scan to eliminate other causes. So far all my tests have come back within normal ranges. I still cannot exercise much because when I try it seems to trigger the burning and pain in my arms. Night time is very scary to me for all my symptoms seem to heighten and I think this brings on some added anxiety which leads to sleeplessness. Well I fired my primary care physician and am scheduled to see someone new next week. Hopefully she will listen to me more intently and have some beneficial suggestions. Hang in everyone, I have to believe we are on the right track and soon someone with some sense will finally listen and do something about these terrible statin drugs. KOOKOO

I've been taking Wellbutrin sr for 3 days, I'm mostly forgetful, irritable, my mind is racing panicky, tremor, nausea ringing in my ears, speedy energy but then when you crash ur sooooooooo tired. jittery.

I have been on Topamax for a little over a year. I've had most of the side effects; tingling, numbness in the fingers, dry mouth, forgetfulness, and weight loss - love the weight loss. All the side effects have sort of slowed down as I've been on the medication longer. The weight loss has slowed and I've even began to get my appetite back- I'm afraid I'm going to start gaining weight now! I've lost about 40 pounds and I needed to lose it, so that was wonderful. I've had a very hard time losing weight all my life so this was wonderful.

I was addicted to Coca Cola and this med also helped me kick that habit because I lost my taste for the carbonation.

Does anyone know if the weight loss usually evens out after about a year or a year and a half? I need to lose about 30 more pounds and was hoping that I would continue losing weight!

Anyway, I was on the Topamax for headaches and it has completely helped that! It has truly been a God-send for me. Other than monthly hormone headaches, I don't get migraines hardly at all!

I am wondering about having my doc up my dosage for the weight loss aspect????

My little boy who is now 4 has been off the Reglan for two years. I really thought my husband and I were doing the right thing by putting him on the Reglan at 8 months because he was vomitting blood. The gastric doctor said he had to be on it plus prevacid .Well I WISH WE HAD KNOWN THE SIDE EFFECTS. Now my son is in the process of going to a Neurologist next week because they think he might have Tardive Dyskinesia . He has the symptoms of it on and off for a year now and the doctors have said it is from stress not possible because all of the stress therapist we have taken him to say he is not stressed. I would like to say one thing do not put your child on this drug because it could be the biggest mistake of your life . This is a disease that can not be curred.

Just resumed my 25mg of toporol XL after a miserable 5 day trial on lisinopril. My main symptoms are PVC's, chest tightness (chronic), lightheadedness. These seem to be somewhat helped by the medication, and I wonder about upping it to 50mg (MD fine with that), but I really don't want to be on it. Originally put on for high BP (150/90), and persistent PVCs. I need to lose about 40 pounds to get the BP back to normal, but if this toporol puts the weight on that is truelly a catch 22. Anyone find any supplements that could be helpful? Please feel free to email me. Thanks Liam

I started singulair in 2003. It seemed like a miracle drug! I had no asthma until feb. 2007.I had really bad asthma I had to start using my pulmo-aid again. Well since 2003 I,ve had very bad leg pain, neuropathy and RLS. I was a sales person. I walked miles and miles every day. I was in so much pain. I am on darvon. My head has a tremor. My hands are shakey.
I started taking cymbalta for depression And had to quit work.I've been off for 4 months. I lost my health Insurance, I couldn,t afford my singulair I started taking Quercitin. It works really well .It's been about 3 weeks since I stopped taking the singulair and guess what? I had my first pain free day sat.april 20 I've been having a lot less pain in my legs!