Twilight zone symptoms and conditions

I was diagnosed with bronchitis a couple of days a go and was given a 5 day course of Levaquin 750mg. The doctor also gave me a prescription for the Z pack in case Levaquin did not work. Before I went to the doctor I had a fever of 102 for 5 days so I was ready to take anything. That evening Nov. 11th 2008 I took my first pill... and my last one. The onset of side effects started within 3 hours. It began with an extreme blinding headache and a very stiff neck. I finally fell asleep and had the most intensely bizarre dreams which I woke up from several times to find my self drenched in sweat. The night sweats were extremely intense and followed me through to the next day. I could not stop sweating... My head was pounding in pain, it felt as if my brain was swelling though my fever had subsided. I proceeded to turn the tv on to try to distract myself, but as I was doing so my mind was racing and I found it very difficult to organize my thoughts. My vision was very isolated meaning that I felt like I had lost my peripheral vision all together. I was unable to read silently without hearing the words in a loud voice in my head...very very strange. I had zero appetite and experienced serious diarrhea the next day. This drug felt overwhelmingly powerful kind of like dropping a nuclear weapon on a small village. I felt like my body was on fire for a moment as if i was given chemo therapy. While trying not to panic I realized that a lot of my joints were cracking. It was then I decided to go online and do some reading about this drug...WOW... I mean WOW... How do scientists manage to create a drug that can actually snap tendons... We can't cure anything but we sure can napalm the hell out of anything. That being said I decided to call my doctor and said WTF were you thinking giving me this!?! Needless to say it took about 60 hours for the one pill to wear off. I am terrified to think what would happen to me if I had finished the 5 day course. I know the one pill caused some damage, hopefully nothing permanent. I am now on the Z pac and it is very mild in comparison. Please listen to your body as I did and immediately discontinue use if you experience any side effects. I firmly believe that this drug is something you take only if you are dying and there are just no alternatives ie Anthrax.

We have all been saying that our issues regard not being informed about all of the possible side effects. And, we know that Singulair works well for some people. Nobody wants to take a good drug away from those for which it probably performs miracles. People who have toxic side effects have a right to know up front.

My observations about montelukast's chemical structure are either general or not quite 100% correct or could be quite vague - so forgive me. I do not claim to be good at organic chemistry. But from doing a little work, I have come up with some observations.

1. It would seem to me that montelukast might work quite well for people who have developed mold category related asthma. I observed that chloroquinolin, a component of montelukast, is a good fungicide effective against Aspergillus, Alternaria, Cladosporium, Penicillium and Candida. Dust mites can only digest if helped by aspergillus so they go into the mold category. Molds produce millions of spores so anyone who lives in contact with mold would be chronically sick from their presence. Then people get hypersensitized to that.

I am probably wrong but I could imagine that montelukast is: 1) a ligand that binds to an empty cysLT1 receptor for a period of time 2) 7-chloroquinolin-2-yl which either acts intact or breaks down into a quinoline fungicide so that it kills the chronic mold/fungus infection and 3) a sulphur/methyl anti-inflammatory component that tells the t-cells that they are not needed so they will die. Wow, that would be great for mold asthma if it was completely non-toxic. It would be also great under controlled circumstances for many people who are mold-miserable. If I am wrong, I better go out into my garage and start inventing such a drug.

This is my visualization to try to explain the side effects of neurotoxicity. So adverse reactions could be to the quinoline component as an allergic reaction or dose related so that it just built up to a toxic level over time. There are many signs that t-cell populations are significantly reduced by montelukast. The fact that the Italians can do it in the test tube might be that it's a chemical component of montelukast designed to cause the t-cells to die.

Montelukast is a large molecule so Artie says it cannot penetrate the blood brain barrier. That would be an argument if nobody was complaining about neuro-psychiatric side effects. The neuro-psychiatric side effects are identical to quinoline and quinolones. When I read about Lariam, it just sounds like a more extreme version of Singulair side effects. Chloroquinolins were used before they invented Lariam, which is stronger. The malaria Plasmodiums became immune. Hallucinations, anxiety, depression, suicidal thoughts are completely consistent in all of the quinoline/quinolones. If montelukast breaks into sub-molecules then quinolines easily penetrate the blood brain barrier.

I find clinical evidence that montelukast may act as more than more molecule. And, that there is a rational for the existence of the chloroquinolin and evidence that it may be the source of toxicity.

I am glad to risk being called crazy. That is what the internet is for. We can present our ideas and discuss. So, just take this with a grain of salt. If I am close to the truth, this post will find it's proper home.

Hey Singulair Friends - My son has been off of it a little over a month and is still complaining of stomach aches. Are any of your kids still complaining of that? I am concerned that maybe there may a bigger underlying issue. Any feedback would be appreciated!

I am 27 years old and have just recently completed six months of lupron. I had my last shot in January 2006. The treatment was for endometriosis. I had been in pain for over 10 years when I finally had a laporoscopy to diagnose the endo. I also experienced "mild" side effects from the lupron. But, let me state first that I CANNOT take any sort of hormonal birth control because of the estrogen. Everytime I have tried BC I have had mini strokes. During my pregnancy I also had a mini stroke due to the increase in estrogen.
While on the lupron, I actually felt better than I have felt in a long time. I had the occassional hot flashes, night sweats, and a lot of weight gain. I gained around 25 pounds in four months. I don't recall any other severe side effects. However, I was also on Elavil (anti-depressant) the entire treatment. So I'm not sure if that helped or not. My problem is that now after being off of lupron, I am having horrible feelings of nausea, dizziness, fatigue and horrible headaches. I went to the doctor today because of an excrutiating headache I have had for three days now. It is a weird headache. It only hurts in one spot on the top right side of my head and hurts when I move my head quickly or move my eyes. The doctor did blood work to check my thyroid and has scheduled a CT scan for next week.
Has anyone ever experienced severe side effects after completing lupron? I am wondering if it is the estrogen coming back. Am I better off to be on the lupron? If anyone has any comments or suggestions, please reply.