I have been taking Topamax for over a year for Bi-polar Disorder and Migraine Headaches. My I have been having Kidney problems since January of last year. Grainular type stones and kidney pain associated with the medication. Now the stones would come and go. I am a disabled veteran so I am dealing with the VA for my health care so it is hard to get appointments and proper care to begin with. I have to weigh the benifit vs. the pain. I was told that the tests were fine and that the meds were causing the stones that we have to cut back the medication. It is kidney pain and uninary tract pain, or manic episodes and migrains until I can fined another mood stabilizer that works as well as topamax.