I have been on effexor for over 2 years. Last year I tried to get off this medication. The doctor never explained what the withdrawl side effects would be like. I was so sick, disorientated, severe numbness in my arms and leg. Electrical shock-like sensations throughout my whole body. If felt at times like someone was driving pins into my head. This went on for days. I went to the pharmacy (was away from my doctor)they said no medication would make me feel like that. Weeks later I still had these symptoms. My doctor suggested an MRI, thinking I had all the symptoms of MS. MRI was clear but migrains came back with a vengence. He suggested starting med again. All symptoms went away. This med is scary. I am going off this stuff for good now. By reading all of your testimonials I now know I'm not crazy. I too put on almost 20 pounds and now have high blood pressure at 36 years old.