I originally posted comments in July, 2005. Since then, I still have most of the side effects I listed. Advair IS NOT helping!!! Trouble sleeping, extreme fatigue, pain in both legs (from thigh to foot), eczema on both hands, can't concentrate, depression/mood swings (I am currently taking 0.5 of clonazepam for anxiety, 1/2 in am 1/2 in PM). So I really don't need the added stress/anxiety of these side effects. The list goes on, but you all know these too well! The only positive I can say is that I haven't gained any weight - it's just the opposite - I don't have an appetite at all! I've only been on the Advair since June and the doctor prescribed 100/50 2x a day. Since I don't have health insurance nor prescrition coverage (and the fact that this crap is not working for me), I only use it 1x every other day. I will be making another appointment to see the doctor soon, because I can't stand this stuff. I have to be very selective on the doctors I see and for what ails me (because of the no health inusrance issue). I was on Flovent and Albuterol for over a year until he switched me. My PCP thinks it's all in my head, nice guy, but terrible bed-side manner. (He's the one that prescribed the clonazepam - been on it for 2 years); went to the ER a few years ago before finally being diagnosed with asthma. I even went to see a psychiatrist! I truly believe I had the astham then, but it went unnoticed. Now I have all these weird side effects - some are new since taking Advair and it doesn't quite register at first, then I blame it on the Advair. I read some comments that it has worked for some people and that's great. But I am not one of the lucky ones. I will go from doctor to doctor, new meds to new meds, etc. until I feel like my old self again. It can't always be like this. Does anyone know of any natural remedies out there? My email is ******. Thanks!