My wife began taking Singulair April 2005 because of allergies (couging with some spitting) and by June when we returned to see the Dr. she was fine but her Dr. wanted to keep her on Singulair. The first of August she began having serious coughing and spitting (mostly at night) and it continues. The x-rays and ct scans show her lungs are okay. My question/concern is the Singulair ad on TV mentions a side effect of upper respitory infection and when I brought this up to the Dr. it was ignored. My wife does pretty well during the day but takes her Singulair at bedtime and either the laying down or the Singulair is causing her to wake up every 2 -3 hours coughing and spitting.