I've been on 300 mg for a while, and am feeling really good. I've lost weight, which has been great! The only strange side effect I'm experiencing is skin irritations on my scalp. Every week I feel like I get a few painful bumps on my head, and then, they go away in a day or two. Some of them are of a fairly decent size. THinking maybe benedryl might help since it does seem like an allergic reaction. I'll check with my doc, but if this is the only side effect, and I feel this good, I'd say I'm pretty happy with it.