I've been on antidepressants for 9 years (I'm 19) and I've tried many; a Buspar side effect is by far, the worst side effect I've ever had to any drug, and I've never been allergic to any medications. About 15 minutes after I had my first dose of this medication (about 30 mg) I experienced tingling and slight numbing and paralysis on one side of my face. please be careful, and stop taking this if you have any strange or immediate side effects.