I would strongly suggest that anyone taking Maxide or the generic medication supplement it with potassium. I know that it is not supposed to deplete the potassium and other electrolytes, but it can. Since potassium is water soluble, the body flushes out what it doesnt need so it wont hurt you and will probably help eliviate a lot of the side effects, namely cramps, dizziness, light-headedness, anxiety, aggitation, fatigue, and so on. Start off with the recomended dosage and increase after a day or so if you dont see results. As soon as I feel any of these side effects, I take potassium until they go away. It takes about an hour for it to get into your system so give it time to work. Most people dont realize the importance of potassium and that most of us are at a deficient of it. Also, magnesium helps the body retain and absorb potassium, so you may need that too. I'm not a dr. I just want to share with others what has helped me. My husband is now a believer since he finally gave in and started taking potassium and hasnt had a migraine since. Until then, he had them almost daily for years and the drs couldnt find a cause and nothing else helped.