My daughter has been on Prednisone for 16 months because of a blo...

My daughter has been on Prednisone for 16 months because of a blood platelet disorder (ITP). She started with 100 mg and has gradually been weaned down to 2 mg. Yesterday, her platelet count dropped quite a bit, so they took her back up to 3 mg. to get the count back up. I have several questions--because she is scared to check for herself. 1st, she has had a "sore" or achey spot on the side of one of her breasts--not a premenstrual sore, just a deep sort of ache. Could this be related to the prednisone? Also, she has had breakthrough bleeding between cycles. Also the pred??? Are there side effects even on this lower dose? She is 25 years old, and this has been a horrific ordeal for her and her new husband (who is incredibly understanding and patient). She is constantly anxious and deals with irrational fears. Frequent mood swings are common. I am sure this is all a result of the long term use of pred., but she so much wants to return to normal again. Has anyone experienced any of these or been on pred for this long? Thank you!