I was using it for acne. I'd been on it about two weeks when I started having sudden high fever and extreme lethary. (Like if I didn't lay down, I'd fall down). I'd hit the bed for several hours, and wake up feeling improved. Then I'd go through the same thing later that night; fever back up and horrific fatigue. I kept thinking I was coming down with something and even remarked that I was glad I was "already on an antibiotic." Then realized my fevers were shortly after my dose. Nurse said "no, that wouldn't do it. I took one more dose to "see" and in addition to the fever going up, that time my lips swelled and itched. Spoke with the Dr. and he said NEVER to use a sulfa med again, as the next reaction could be quite dangerous.