I have been on Advair 250/50 for the past few months. It stopped the chronic short coughs and helped my asthma but I started having more problems with my throat. I am a professional vocalist and lost my voice. Went to my ENT and they found that I had an infection on my vocal chords. I stopped Advair yesterday and am going to check for something different. I am amazed at how little my GP knew re: Advair. I asked him this question two months ago and he said I could keep taking Advair without any problems indefinitely. A few minutes on the internet told me different. He must not have internet access or maybe he is using dial-up.