I was given Sulfameth/Trimethoprim for a suspected spider bite that became infected. My prescription was one tablet by mouth twice a day for 10 days. Seven days after taking my first tablet I began to feel itchy all over my body. The next morning I woke and had hives from my feet to my ears. I went the urgent care clinic and they gave me some strong antihistamines. The next day my condition was worse and I went back to the urgent care clinic and was injected with steroids. The next day my condition was even worse; the hives were horrible, itchy, red and purple patches ALL over my body and I was feeling tightening in my throat. I immediately went to ER and was admitted.
I spent 2 days in the hospital receiving steriods and fluids by IV. The thing that surprised me about this allergy was the delay from first taking the medication to the first signs that something was not right.