I am on Advair 250/50 and I want to QUIT NOW. At first it worked great, still does on my asthma, but for the past month, I have gotten so jittery, nervious, snappy and my heart rate at resting is racing at 115-120 bpm! I hate feeling like im about to drop dead. Ive called my doctor and am begging him to switch me to flovent instead. Flovent doesnt have the salmetrol and Im sure its the salmetrol that is causing my crazy jitters. I have cut my dosage to one a day and I hope that my Monday I will be off it altogether.