I am on my fourth day weaning off Wellbutrin after two weeks of every other day. (I have been on 150 mg.) I went on it to combat sexual/lack of energy side effects of Paxil. Went off Paxil (which was HELL) in Sept. Liked the energizing effects of Wellbutrin, but in the past few months I have been very, very irritable, argumentative, prone to road-rage, etc. I am getting married in four months and want to make it to my wedding day! I also have been getting heart palpitations, itchiness and insomnia. But the killer for me is the mind racing and irritability. I am incredibly fatigued without my "speed," but I'm looking forward to being a sweet, if a bit sleepy, person again.