I have taken Fluoxetine for Depression/Panic Disorder for approximately 4 years, prior to that I had taken Paxil with terrifing results. On Paxil, I had terrible nightmares, sleeplessness and irratability. However, since changing to Fluoxetine I have been doing great. I still have occasional sleepless nights or difficulty staying asleep. I will start in the middle of the night to wake, I can usually go back to sleep within a few moments, but to do this continually through the night can defeat a good nights rest.
Also, since I am a female I have noticed that Fluoxetine has helped with PMDD, (Premenstral problems) however if I skip a dose accidentally or not, then I'm an emotional basket case. And these emotional distruptions can last up to a week or more. Just thought other women would like the info.