I did a ten day course of cipro for a UTI. at about day 6 my thighs started hurting a little and by day ten my calves hurt as well. a few days after that my achilles tendons were killing me and I was put on prednisone for ten days, it actually helped the pain. after the steroid course ended the pain returned and now encompassed the bottom of my feet, ankels, knees, left shoulder, and carpal tunnel in both wrists. My DR said he wasn't sure what to do when this kind of reaction to cipro occurs. as of now I am almost disabled, I can stand only for a few minutes at a time, and I am in constant pain especially in my feet. I don't know what the solution to this is, but I think that Bayer should be held responsible when their product disables someone. I am not trashing Bayer, cipro did exactly what it was supposed to do for the UTI, I just had a bad reaction to it.