I have been Advair 500/50 for 4 years with results so profound it enabled me to join a local volunteer fire department rescue squad where I am an EMT & officer . So much for the good news. The bruising, constant tiredness, sinus infections, earaches, mood swings and especially the excruciating joint pains I accepted as part of aging. The hip joint and lower back pain became part of my daily life. Drugs, steroid injections, chiropractic with electrical stimulation, exercise, hot tub soaks @ 2 in the morning were usless. I found this website 4 days ago and have been Advair free for 3 days. The asthma is ok, the pains are gone, I am energetic, and feel much calmer. I feel 10 yrs younger than my 53 years.