Is it possible to be alergic to this medication,when used with a ...

Is it possible to be alergic to this medication,when used with a Hollister 8485 pouch The Hollister nurse didn't say any thing about this,and I thought I would ask else where. I remove the pouch every 3rd day,clean the area around the stoma with Dial soap, dry the skin,apply the powder, leaving a thin coat,then place the pouch in position.It has shown improvement,but I'm starting my 3rd container,and It isn't clear yet! What thoughts do you have on this? Thanks for your time oldguy@socket.net