I have had a "reverse" side effect. I have been taking Allegra 60 mg for years, without any apparent side effects. Then I tried to discontinue the medication, and I started itching ALL over my body. The itching begins immediately, and will stop as soon as I resume the medication. This has happened on more than one occasion, when I tried to "quit". Is there any way off this stuff, or do you have to use it for life?