Toprol is a beta blocker and so high doses will really monkey with your hormones. A beta blocker stops the action of adrenaline and tons of other body chemicals that are very necessary for certain functions that are unfortunately also controlled by the same body chemicals that cause the heart to beat very fast and blood pressure to raise. So you can expect to have symptoms that mimic hormone imbalances like hypothyroid or PMS because it all comes down to hormones.
If, however, you're getting GERD, then it means your liver is veyr much overwhelmed by all the bad foods, phony fats and pharmeceuticals you've been taking. ******
Hope that helps! :)