Lipitor has caused me serious colon problems. I was having severe cramping and bowel movements. The colon contractions were so severe that I would begin vomiting, even though I was not nauseated. After 2 or 3 hours of these bouts, occurring every 1 to 3 days, I would be so weak I would have to go to bed. Then severe weakness overtook my entire system. I have no appetite and have lost 19 pounds since January. Food has no taste and after forcing eating, I don't want anything else to eat after 3 bites. CT scan showed severe edema in the cecum and descending colon plus diffuse inflammation of remainder of the colon. Quit taking Lipitor and cramping subsided almost immediately, but now have almost constant diarrhea. I WILL NEVER TAKE STATINS AGAIN!!!