I have been taking prednisone for about a month now due to an outbreak of ulcerative colitis. I started off on 50 mg per day and have been weaning off week by week going to 40, 30 and now am at 20mg. The side effects I've experienced so far are a weight gain of 10 pounds, increased appetite and thirst, excess sweating, mood swings, and worst of all fatness added to my face and hips. I would not recommend being relient on this drug but most likely like me, you have no choice. I am only 14 years old, but hopefully this will help someone.