My daughter is 8 years old. She has been on Advair for about three years (maybe four) and I have noticed over the years that she seems very irritable. This symptom is getting worse as time goes on, and I think it will develop into depression if I don't do something soon. Another symptom is weight gain. When my daughter started Advair she was at a normal weight for her age and had a normal appetite (her father and I are both normal weight). Now she is significantly overweight and never seems full. She is always saying" I'm still hungry". I have discussed these problems with her Pediatrician and he tells me not to worry, and that there is not enough steroid in Advair to cause the problems that I am concerned about. I trust her DR. but I am worried that he is ignoring significant problems. Has anyone else had these types of side effects or am I indeed the overimaginative mother that the Dr. thinks I am?