I took a 7-day course of Biaxin and didn't notice anything during that time. Had bronchitis and got better. After the seven days my taste buds disappeared and I cannot taste. My entire mouth is sore, including tongue. My mouth and tongue feel like a very bad tongue burn. I have a lot of metal in my mouth because I have a partial plate and made mostly of metal in the roof of my mouth. So maybe the taste everyone talks about is a metallic taste. But I tell you this, it hurts. I'm just wondering if my taste will return. Has been like this from 7/01 and it is now 13 days later.