I have had migraine for 26 years, I took depakote for 12 years before taking topamax. Now the sensation of what I feel in my mouth is wrong. It helped with my migraine but now I have something that every doctor I've seen hasn't heard of. It made me loose 85 lbs., quit sweating, not sleep.... Doctors give me phych drugs to mask the mouth thing, but I'm allergic I'll take migraine over all the things extra this drug has given me also. I think it is dangerous because I QUIT eating I had to make myself eat. This is hard to do when you are absolutely not hungry. Has anyone else had the mouth sensory reaction?