I switched from Prevacid to Nexium....that was a mistake. Like others have said on here, it is like taking no pill at all. I still get chest pains that wake me up in the middle of the night. These pills have made me lose tons of sleep. Something new now, is actually having intense heartburn, taste of acid, and dry mouth, along with all of the other symptoms. (Constant nausea, etc.) One thing that helped me while stuck on Nexium was a teaspoon of apple cidar vinegar. Sounds nuts but research it and read the results! Anyway, I'm going to the Dr. today to hopefully switch to Aciphex.