I have been taking Toprol, with Lipitor for 2 months for high BP and have gained weight considerably. I run on a treadmill/outdoors 4 times a week and can not get past the shortness of breath. The weight gain is mostly in my upper torso area. I have been athletic all my life and this is a new occurence. Additionally, I do not sleep well and I sweat profusely during the night to the point that my pillow and sheets are soaked. I plan to speak with my doctor soon for a replacement.