Started Metylpred on 8/11/06 after having a reaction to Avelox combined with Allegra-D both of which I was on for sinus infection. The reaction to Avelox was almost a nervous system breakdown where I started shaking uncontroillably and my BP was sky high. Metylpred has not done much better for me. Have very high anxiety, lore weakness/soreness, headaches. Went back to DR and I am to stop taking immediately. The side effects to this are worse than the sinus infection that I started taking all this for.