I have had both the Imitrex pill and injection . The shot seemed to work alot better with the migraine pain and less for my nausea. The E.R. Doctor gave me two of the Imitrex pills for future Migraines. About 3 months went by and it hit me while taking my husbands 87 year old grandmother and my 3 yeat old son camping. I felt the shooting pain and blurred vision in my right eye and luckily had my pill to try. This was the first time I had tried the pill and was not even prepared for the what was about to happen. After 15 min. of the taking the pill I felt so hot like someone had just shot boiling water in my veins. There was no way I could have did anything the pain, nausea, and numbness were much more for me to handle. My husband had to come had stay with us and in one hour my migraine was tolerable, but the imitrex still left me very uncomfortable.