I started taking 25 mg of Topamax in March 2006, slight reduction in migranes. July 1 neurologist increased meds to decrease migranes weekly to max of 100 mg, 2 weeks later and until this day, my problems have been horrendous. It has taken me 6 weeks to realize that they are due to the topamax. Extreme pain in lower left side, bladder infection like symptoms without an infection; walking around in a stupor; feel flu like, unable to think clearly; naseau; can not get out of bed; missed a week of work because I felt so unwell. I am slowly going off the topamax, although the urologist states "there is no correlation between your pain and the meds"; and it took two calls to the neurologist before anyone would listen to my plight. How long will it take to get this poison out of my system. I would rather have migranes every day than feel like I have been changed into an entirely different person emotionally and so unwell physically that nothing else matters. I was working two high pressure jobs, ready to complete another degree, and functioning a completely normal pleasant life with my family and friends. Topamax has taken care of diminishing all of this for me. My credibility in a position where I must think clearly and responsibility in my family where I am depended upon for much are sorely effected by this horrid medication. I believe it is very interesting that the side effects for migrane patients vs. those who take it for epilepsy and seizure are as different as night and day -- but it's the same medication. Kind of like me pre and post Topamax medication!!!!!