Put on 80 mg a day because of back pain. Did not sleep for 7 days, could not get a hold of a doctor to stop. Finally, got ahold of GP who put me on anti-depressants. This is like throwing gasoline on a fire-did not sleep more than 20 minutes at a time for another 5 days. Now getting back to normal but still have foot and ankle pain. Back feels the same as before I started it. It sounds like reactions are very person and dose specific. DO NOT TAKE THIS DRUG IF YOU POSSIBLY AVOID IT-If you start, have 3rd party evaluate side effects. You can not self-diagnose that you are in trouble. It is like you are in a fog and you can not think straight enough to gauge what is happening!