I orignally started taking 25 mg for chronic hives after a roller coaster w/any thing containing blue dye, prednizone, allegra, claritan. Finally I stopped taking all colored meds only white or pale. I have a lot of wgt gain since this ordeal started in Nov. I did not know Doxepin could cause wgt gain. I am now taking 50 mg at night for insomnia and it does have an antihystamine in it. I think I am going to cut back to 25 mg again and get off this. One Dr. told me anything with antihystames are a wgt gainer. I also take Zoloft in the a.m. which helps okay and Doxepin can also be used for that but mainly helps me sleep and gain wgt :-)