Just recently, my pharmacist re-filled my Synthroid prescription with a substitute (Levothroid). After taking it for about a week, I started to have AWFUL stomach pains. I was constantly nauseous. I asked my doctor and he said it was probably just acid indigestion and to take some over the counter remedies. I started to take Maalox and Alka-Seltzer, but they only seemed to help for about 30 minutes to an hour before the pain came back again. I asked if it could have anything to do with the Levothroid and he simply said no (Grrrrr!). I switched back to the Synthroid and the pains went away within a couple weeks.