I was recently hospitalized for an acute episode of polymyalgia rheumatica and discharged on 60mg of prednisone/day. I have taken smaller doses in the past but this amount has really affected me negatively. For the first 2 weeks, I felt an inability to think clearly. The dose has been reduced to 50mg/day and the thinking has improved. After 1 month, I have the moon face and severe bruising. However, my biggest concern is that I am now experiencing extreme muscle weakness. I feel like my muscles are detiorating. My dose is being reduced to 45mg/day now. Has anyone experiences a similar side effect?