Wow! I am also pleased to have found this site! I am a 41 yr old woman with MVP, diagnosed about 2 years ago. I was put on 25 mg of Toprol, and almost immediately began experiencing fatigue and apathy. It did, however, reduce my syptoms of MVP.
After awhile, I questioned the fatigue and modest weight gain and my MD allowed me to cut my rx in half. I was still feeling all day fatigue, which I cannt afford as a full time working Mom. (Who can, really!?) I was really over people telling me "you look tired", even on days I felt fine. I would wake up sometimes and be shocked at how exhausted my face looked. Had I really aged that much in two years!?
My MD finally told me that if my next heart scan looked OK I could try going off the drug. I cant wait! The cure IS really worse than the disease, for me at least! I would rather deal with palpitations and occasional twinges than this fatigue anyday, as long as I feel confident there is not blockage, which there is not, so far.