I was prescribed Sulfameth/Trimthoprim 800/160 by an ER Dr for UTI and took for 10 days as directed. I the drug did make me nausiated but if it was going to help my infection I thought I could indure that. It cleared up the infrection ok but within a week I broke out in a TERRIBLE rash from head to toe. I have never itched so badly in all of my life! I had no idea what it was and used every over the counter remedy until I was able to see my doctor who told me it was a delayed allergic reaction to the sulfur drug and gave me a steriod shot and a histamine pill to take. It has been the worse for me and I will NEVER take a sulfur drug again in my life especially this one.