My son is 12 years old and was put on prednisone for poison ivy. He took the pills for one day(2 a day) and he woke up at 4:30am with severe eye pain. His doctor thinks we should ignore it and continue to give him the medication! I did not continue to give him the medication. This is listed as one of the SERIOUS side effects. I have an appointment with his eye doctor today and will post an update tomorrow.