Well I have been taking Topamax for 3 weeks tomorrow and so far the side effects have not been that bad for me. I have experienced a little bit of most of the ones I have heard about: loss of appetite, weightloss, numbness/tingling in hands/feet, off tasting carbonated beverages, fatigue, mood swings, increased thirst, increased perspiration. But they haven't been that extreme for me. The pros have really outweighed the cons so far. I have only had 1 migraine since taking the Topamax, and it was a few days after starting it. I am upping to 75 mils tomorrow so we'll see how I feel about it after that, but so far so good. I think that it is really important to remember that everyone's body chemistry is sooo different and we are all going to react differently to this drug. I have pretty much found that people either love this drug or they hate it. But it is really nice to be able to get feedback from other people to see if the side effects we are experiencing are "normal". When 50 some odd other people are experiencing the same thing on this drug then I think it's a pretty safe assumption that it is related to the drug, whether or not the doctors want to claim it is or not.