I take toprol 2x per day(50 mg/100 total). I get extreme headaches all over my head. I also get panic attacks(feel like I need to call 911 due to increased heart rate) at night and can't sleep. I feel nauseous at bedtime, and the feeling continues through mid-morning. I used to work, work, work, but now I worry and am very lethargic. When I work hard, my heart races and again I feel nauseous. I have had cardio-version two times now to get my heart back in rhythm. I am 49 years old. These problems run in my family. My mother's grandmother died at the age of 49 and my mom has had cardio-verson 4 times now. Who wouldn't worry? I am also on tambicor, and aspirin once a day. I have gained weight! Just what I needed.