I was on Prednisone for about 4 weeks. 60mg/day first 2 weeks, followed by 40mg/day last 2 weeks. My dose was extremely high (only weighing 105lbs in the beginning) and i had extreme side effects! I gained 20lbs in the first week and a half, my face doubled in size, very depressed, and i got to the point i could only walk a couple of feet then the pain was just to intense! the last time i went to the doctor he didn't quite believe the extent of my side effects and - i quote "well your only on 10's just imagine if you had to take 40mg a day!" so i took my new scrip to the pharmacy and noticed that the new bottle said 20mg. i told the pharmacist that this is wrong i'm suppose to be taking 10mg twice a day.!? he then informs me i must be wrong - that i've always been on 20's (i started with 3 a day then worked down to 2 a day, now i was suppose to work down to one a day over the next 2 weeks!) i then call my dr and he tells me he made a mistake and we'll have to figure it out next week when i'm scheduled and to continue what i was taking!!! well if any of you have had the muscle pain from this drug its almost worse then having the problem you started with! (although i probably wouldn't have lived without it, it was driving me to a point that dying almost seemed better!) well i completely quit the day i found out i was taking double the dose my dr thought i was taking and it has been a month and a half since then. i still have constant muscle pain, stomach pain, and practically no immune system anymore! i don't know how long this will last....but i really hope it ends soon!!