I have been on Topamax foe about five months now and it has changed my life! my migraines were so terrible before that I could barley function and took migraine medicationsthree -five times a week. The Topamax has reduced my headaches by about 75% and now an over the counter medication can do the trick if I feel a headache coming on most of the time. Bonus, I lost 30 pounds that I had been hanging on to since my son was born three years ago. I take 100 mg. 2 times a day.