I took my son to the dr. yesterday and he had his first singulair pill last night. about 2 hours later, he told me that his throat hurt. Now today, my 12 year old was very irritable and upset. Everything that he says to me is hateful, and this is not my boy at all. I am taking him off of this medication right now. There is too many other forms of medicine to control his asthma.If your child appears to be more irritable than usual, you can bet it is from this stuff.