I have taken neurontin in the past after being diagnosed as bipolar. It caused my depression to worsen and I became suicidal I also gained 100 pounds. For those being treated for irritable bowel syndrome and or depression a wheat allergy can cause both symptoms. I stopped eating all wheat products and no longer have IBS or depression. Also of interest for people with joint and muscle pain, there is a chemical in white potatoes, tomatoes, green peppers, and eggplant that can make pain worse.